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Updated: Jun 25, 2026

Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models

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Published on: March 13, 2018

Nuclear imaging and cervical cancer.

P W Grigsby¹

¹Department of Radiation Oncology, Division of Nuclear Medicine, Mallinckrodt Institute of Radiology, Department of Obstetrics and Gynecology, Alvin J. Siteman Cancer Center, Washington University Medical Center, St. Louis, MO 63110, USA. pgrigsby@wustl.edu

Minerva Ginecologica

|February 11, 2009

Summary

Advanced imaging techniques like PET/CT and SPECT/CT improve cervical cancer staging and treatment. These methods enhance diagnostic accuracy, guide therapy selection, and enable objective long-term surveillance for patients.

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Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

Published on: October 20, 2010

Area of Science:

Oncology
Radiology
Medical Imaging

Background:

Cervical cancer staging traditionally relies on the International Federation of Gynecology and Obstetrics (FIGO) clinical staging system.
Conventional radiographic studies like chest X-ray, intravenous urogram, and skeletal X-rays have been used but do not alter clinical stage.
Advanced imaging modalities are increasingly utilized to complement traditional methods in evaluating cervical cancer.

Purpose of the Study:

To review the evolution and impact of imaging studies in the diagnosis and staging of cervical cancer.
To highlight the role of advanced imaging techniques in guiding therapy and monitoring treatment response.
To emphasize the benefits of modern imaging in improving patient outcomes and surveillance.

Main Methods:

Review of traditional radiographic imaging studies (chest X-ray, intravenous urogram, skeletal X-rays, barium enema, lymphangiogram).
Evaluation of the integration and utility of computed tomography (CT) and magnetic resonance imaging (MRI).
Focus on the application of advanced modalities: positron emission tomography/computed tomography (PET/CT) and single photon emission computed tomography/computed tomography (SPECT/CT).

Main Results:

Newer imaging modalities like PET/CT and SPECT/CT offer enhanced accuracy in diagnosing and staging invasive cervical cancer.
These advanced techniques improve the precision of therapy selection and guidance.
They reduce uncertainty in monitoring treatment response and provide objective data for long-term surveillance.

Conclusions:

Advanced imaging techniques, particularly PET/CT and SPECT/CT, are crucial for comprehensive cervical cancer management.
These modalities significantly improve diagnostic accuracy, therapeutic guidance, and patient monitoring.
The adoption of these technologies facilitates more objective and effective long-term surveillance of cervical cancer patients.