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Related Concept Videos

Gene Families01:57

Gene Families

Gene families consist of groups of genes proposed to have originated from a common ancestor. Typically these arise through events in which a gene or genes are mistakenly duplicated during cell division. Unlike their parent genes (which are subject to selection pressure to maintain function), these gene copies do not need to preserve their sequences and may evolve at a relatively faster rate.
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
Gene Families01:57

Gene Families

Gene families consist of groups of genes proposed to have originated from a common ancestor. Typically these arise through events in which a gene or genes are mistakenly duplicated during cell division. Unlike their parent genes (which are subject to selection pressure to maintain function), these gene copies do not need to preserve their sequences and may evolve at a relatively faster rate.
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
Phylogenetic Trees03:21

Phylogenetic Trees

Phylogenetic trees come in many forms. It matters in which sequence the organisms are arranged from the bottom to the top of the tree, but the branches can rotate at their nodes without altering the information. The lines connecting individual nodes can be straight, angled, or even curved.The length of the branches can depict time or the relative amount of change among organisms. For instance, the branch length might indicate the number of amino acid changes in the sequence that underlies the...
Phylogenetic Trees03:21

Phylogenetic Trees

Phylogenetic trees come in many forms. It matters in which sequence the organisms are arranged from the bottom to the top of the tree, but the branches can rotate at their nodes without altering the information. The lines connecting individual nodes can be straight, angled, or even curved.The length of the branches can depict time or the relative amount of change among organisms. For instance, the branch length might indicate the number of amino acid changes in the sequence that underlies the...
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...

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Related Experiment Video

Updated: Jun 25, 2026

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
08:57

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Published on: August 14, 2018

Maximum gene-support tree.

Yunfeng Shan1, Xiu-Qing Li

  • 1Molecular Genetics Laboratory, Potato Research Centre, Agriculture and Agri-Food Canada, 850 Lincoln Rd, P.O. Box 20280, Fredericton, New Brunswick, E3B 4Z7, Canada.

Evolutionary Bioinformatics Online
|February 11, 2009
PubMed
Summary
This summary is machine-generated.

The majority of orthologous genes maintain species relationships, with the "maximum gene-support tree" accurately reflecting evolutionary history across yeasts, viruses, and plants. This highlights conserved genetic information in phylogenetic studies.

Keywords:
gene evolutiongenomemolecular phylogenytrue tree

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Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine
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Last Updated: Jun 25, 2026

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
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Published on: August 14, 2018

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Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline
10:44

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline

Published on: December 7, 2021

Area of Science:

  • Molecular Evolution
  • Phylogenetics
  • Genomics

Background:

  • Gene and genome diversification occurs during evolution.
  • The extent to which genes retain ancestral relationships across species remains an open question.
  • Model organisms like yeasts, viruses, and plants are crucial for phylogenetic research.

Purpose of the Study:

  • To investigate the degree of divergence of orthologous genes within genomes.
  • To determine if gene trees can accurately represent species' true phylogenetic relationships.
  • To identify the most reliable gene-based phylogenetic reconstruction method.

Main Methods:

  • Generated single gene trees for seven yeast and nine baculovirus species using orthologous genes.
  • Utilized homologous genes from seven plant species for validation.
  • Employed four phylogenetic algorithms: maximum parsimony (MP), minimum evolution (ME), maximum likelihood (ML), and neighbor-joining (NJ).
  • Reconstructed trees with and without weighting gene sequence lengths.

Main Results:

  • No single gene consistently produced the true tree across all algorithms.
  • The 'maximum gene-support tree' (MGS tree), representing the most frequent gene tree, consistently identified the true phylogenetic tree in yeasts, baculoviruses, and plants.
  • Weighted MGS trees (WMGS) also demonstrated high accuracy.
  • Higher gene similarity was observed between genetically closer species.

Conclusions:

  • The true phylogenetic relationship among species is largely maintained by the majority of orthologous genes.
  • The maximum gene-support tree is a robust indicator of species phylogenetic relationships.
  • Gene similarity correlates with genetic distance between species.