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Updated: Jun 25, 2026

Iridium(III) Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II
Published on: July 7, 2015
Cyclometalated platinum(II) complexes as highly sensitive luminescent switch-on probes for practical application in
Peng Wu1, Ella Lai-Ming Wong, Dik-Lung Ma
1Department of Chemistry and Open Laboratory of Chemical Biology, The Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, PR China.
Abstract:
Protein-staining platinum: The luminescent switch-on characteristic of the platinum(II) complex can be utilized for staining a series of proteins in sodium dodecyl sulfate-polyarcylamide gels, to give emissive gel images directly under UV light (see figure). The detection sensitivity for BSA protein is down to 6.0 ng, revealing potential practical applications of luminescent platinum(II) complexes in the luminescent signaling of biomolecules.
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