[Risk factors of TT virus infection in children up to 3 years]

Significant frequency of TT virus (TTV) infections and its unclear pathogenetic role are purposes for which investigators are interested in theme of spread of the virus. It is considered parenteral way of TTV spread, oral-fecal, droplets, vertical, by breastfeeding and other ways.

To estimate the risk of TTV infection by various ways and to asses the risk factors of infection.

To the analysis were enrolled 55 patients, in 27 (49%) of them we confirmed TTV infection (polymerase chain reaction method with two primers sets). We analyzed frequency of infections dependence on risk factors vertical, parenteral, and enteral infections.

Disturbances in pregnancy or delivery were not connect to frequency of TTV infections. We're not confirming this frequency dependence on number of past hospitalizations but it was dependence between frequency of TTV infections and chronic diseases and mental-physical retardation of children (p=0.077; p=0.01). It was not confirming significant differences in depend on dwelling place. Children from worse social conditions were infected more often (p=0.05). It was not significant dependence between frequency of TTV infections and breastfeeding. It was confirmed that in children of parents with chronic diseases and children with brothers and sisters with chronic diseases are infected more often (for mothers p=0.054; fathers p=0.04, brothers or sisters p=0.062).

TTV infections are more frequent in infants and young children exposed to often contacts with medical environment, children from poor social conditions and with chronic diseases in near family.