[Primary and secondary prevention of sudden cardiac death in the ICD Registry-Latin America]

Jose L Ramos1, Claudio Muratore, José C Pachón Mateos

  • 1Hospital Italiano, Rosario, Argentina. jlramos@ciudad.com.ar

Insights

This study compared primary versus secondary prevention for sudden cardiac death patients in Latin America. While secondary prevention patients received more appropriate therapies, mortality and hospitalization rates were similar in both groups over a short follow-up.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Public Health

Background:

  • Sudden cardiac death (SCD) remains a significant cause of mortality worldwide.
  • Implantable cardioverter-defibrillators (ICDs) are crucial for preventing SCD through primary and secondary prevention strategies.
  • Limited data exists on the characteristics and outcomes of ICD recipients in Latin America.

Purpose of the Study:

  • To compare the clinical characteristics of patients receiving ICDs for primary versus secondary prevention of SCD.
  • To evaluate follow-up outcomes, including therapies, hospitalizations, and mortality, in these two patient groups within the Latin American ICD Registry.

Main Methods:

  • Observational study design utilizing data from the Latin American ICD Registry.
  • Collection of demographic, clinical, and device-related data at implant.
  • Evaluation of ICD therapies, hospitalizations, and mortality during the follow-up period.

Main Results:

  • 507 patients were analyzed; 189 for primary prevention and 318 for secondary prevention.
  • Primary prevention patients were older, predominantly male, and had lower left ventricular ejection fraction (LVEF).
  • Similar rates of mortality and hospitalization were observed between groups; secondary prevention showed higher appropriate ICD therapies.

Conclusions:

  • This study provides the first insights into primary prevention ICD patients in Latin America.
  • Short-term follow-up revealed no significant differences in mortality or hospitalization between primary and secondary prevention groups.
  • Findings highlight the need for further research into long-term outcomes and tailored strategies in this region.
Abstract

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