[Primary and secondary prevention of sudden cardiac death in the ICD Registry-Latin America]
Jose L Ramos1, Claudio Muratore, José C Pachón Mateos
1Hospital Italiano, Rosario, Argentina. jlramos@ciudad.com.ar
Insights
This study compared primary versus secondary prevention for sudden cardiac death patients in Latin America. While secondary prevention patients received more appropriate therapies, mortality and hospitalization rates were similar in both groups over a short follow-up.
Area of Science:
- Cardiology
- Electrophysiology
- Public Health
Background:
- Sudden cardiac death (SCD) remains a significant cause of mortality worldwide.
- Implantable cardioverter-defibrillators (ICDs) are crucial for preventing SCD through primary and secondary prevention strategies.
- Limited data exists on the characteristics and outcomes of ICD recipients in Latin America.
Purpose of the Study:
- To compare the clinical characteristics of patients receiving ICDs for primary versus secondary prevention of SCD.
- To evaluate follow-up outcomes, including therapies, hospitalizations, and mortality, in these two patient groups within the Latin American ICD Registry.
Main Methods:
- Observational study design utilizing data from the Latin American ICD Registry.
- Collection of demographic, clinical, and device-related data at implant.
- Evaluation of ICD therapies, hospitalizations, and mortality during the follow-up period.
Main Results:
- 507 patients were analyzed; 189 for primary prevention and 318 for secondary prevention.
- Primary prevention patients were older, predominantly male, and had lower left ventricular ejection fraction (LVEF).
- Similar rates of mortality and hospitalization were observed between groups; secondary prevention showed higher appropriate ICD therapies.
Conclusions:
- This study provides the first insights into primary prevention ICD patients in Latin America.
- Short-term follow-up revealed no significant differences in mortality or hospitalization between primary and secondary prevention groups.
- Findings highlight the need for further research into long-term outcomes and tailored strategies in this region.
Introduction And Objectives:
The ICD Registry is an observational study conducted in Latin America to collect data on indications and follow-up care for primary or secondary prevention of sudden cardiac death patients. The objective of this study is to compare and evaluate the characteristics of primary versus secondary prevention in the patient population enrolled in the registry.
Methods:
Demographic data, indication, etiology, NYHA functional class and left ventricular ejection fraction (LVEF), pharmacological treatment at implant and the type of ICD implanted were also collected. During the follow-up period the ICD therapies delivered, patient hospitalizations and mortality were evaluated.
Results:
507 patients were evaluated. Average age 60 +/- 14 years old, 78% male. Coronary heart disease was the most common etiology (43.6%). NYHA Functional Class I/II at the time of implant (73.6%). Average LVEF was 34 +/- 16%. Out of 507 patients, 189 received an ICD for primary prevention; 318 for secondary prevention. Primary prevention patients were older, predominantly male and had a lower EF. The rate of mortality and hospitalizations were similar between both groups with a higher rate of appropriate therapies in secondary prevention patients.
Conclusions:
This is the first study to demonstrate clinical characteristics of primary prevention patients in Latin America. There were no significant statistically differences in a short follow-up period in mortality or hospitalization as compared to the secondary prevention patient population in the Registry.
Related Concept Videos
Coronary Artery Disease IV: Preventive Measures
Cardiopulmonary Resuscitation III: AED Use
Cardiomyopathy V: Interprofessional Care
Introduction Cardiac Emergencies
Cardiopulmonary Resuscitation I: Adult
Cardiomyopathy III: Hypertrophic Cardiomyopathy

