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Allergic bronchopulmonary aspergillosis complicating childhood asthma

Sunil K Chhabra1, Sandeep Sahay, Karthikeyan Ramaraju

  • 1Department of Cardiorespiratory Physiology, Clinical Research Centre, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India. skchhabra@mailcity.com

Indian Journal of Pediatrics
|February 12, 2009
PubMed

Insights

Allergic bronchopulmonary aspergillosis (ABPA) is rare in children with asthma. This study highlights two pediatric cases, emphasizing the need for ABPA consideration in severe pediatric asthma.

Area of Science:

  • Pulmonology
  • Pediatric Allergy & Immunology
  • Infectious Diseases

Background:

  • Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity pulmonary disorder.
  • ABPA commonly complicates asthma in adults, but is infrequently associated with childhood asthma.

Observation:

  • Two pediatric cases are presented: a 4.5-year-old boy with severe asthma and a 12-year-old girl with a history of fleeting chest radiograph opacities.
  • Both patients exhibited symptoms suggestive of severe asthma exacerbations.

Findings:

  • Both children were diagnosed with Allergic bronchopulmonary aspergillosis (ABPA).
  • The diagnosis was confirmed through clinical presentation, immunological markers, and radiological findings.

Implications:

  • This case series underscores the importance of considering ABPA in the differential diagnosis of severe or refractory asthma in children.
  • Early diagnosis and management of ABPA in pediatric patients can prevent long-term lung damage and improve asthma control.

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