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EEG Mu Rhythm in Typical and Atypical Development

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Electroencephalographic abnormalities during sleep in children with developmental speech-language disorders: a

Bronwyn Parry-Fielder¹, Kevin Collins, John Fisher

¹Royal Children's Hospital, Melbourne, Australia.

Developmental Medicine and Child Neurology

|February 12, 2009

Summary

This study found no strong link between epileptiform activity on electroencephalograms (EEGs) and severe developmental speech-language disorder (DSLD) in children. Epileptiform EEG activity was, however, associated with lower performance IQ scores.

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Area of Science:

Neuroscience
Developmental Psychology
Speech-Language Pathology

Background:

Previous research suggested a correlation between epileptiform activity on electroencephalograms (EEGs) and developmental speech-language disorder (DSLD).
The precise nature and strength of this association remain subjects of investigation, particularly in well-defined pediatric cohorts.

Purpose of the Study:

To investigate the strength of the association between epileptiform EEG activity and severe DSLD in children.
To compare EEG abnormality frequencies between language-normal children and those with severe DSLD.

Main Methods:

A cohort of 45 language-normal children and 54 children with severe DSLD underwent sedated sleep EEGs.
Children with DSLD received comprehensive speech-language, hearing, and psychological assessments.
DSLD was defined by scores at least 2 standard deviations below the mean on speech-language measures with a performance IQ of at least 80.

Main Results:

The study did not support a strong association between abnormal EEG findings and DSLD.
A weak, non-significant relationship was observed between DSLD and epileptiform EEG activity.
Epileptiform EEG activity was significantly associated with lower performance IQ (p=0.04).

Conclusions:

Previously reported strong associations between epileptiform activity and DSLD are questioned by these findings.
The results suggest that the association may be weaker than previously thought, especially in purer cohorts of children with severe language impairments and without seizures.