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Asthma and protracted bronchitis: who fares better during an acute respiratory infection?
Helen L Petsky1, Jason P Acworth, Ronald Clark
1Department of Respiratory Medicine, Royal Children's Hospital, Queensland, Australia. helen_petsky@health.qld.gov.au
Insights
Children with protracted bronchitis experience more severe acute respiratory infections (ARI) than those with asthma or healthy controls, with prolonged cough symptoms lasting up to 14 days.
Area of Science:
- Pediatric respiratory health
- Infectious disease epidemiology
Background:
- Acute respiratory infections (ARI) are prevalent in children, causing symptoms that can persist for weeks.
- Understanding symptom severity differences in pediatric ARI is crucial for effective management.
Purpose of the Study:
- To compare the severity of acute respiratory infections (ARI) in children with asthma versus those with protracted bronchitis and healthy controls.
Main Methods:
- Parents prospectively recorded ARI symptom severity using the Canadian acute respiratory illness and flu scale (CARIFS) and a cough diary.
- Data were collected on days 1-7, 10, and 14 of illness for age- and season-matched children.
Main Results:
- Children with protracted bronchitis showed significantly higher CARIFS scores on days 10 and 14 compared to children with asthma and controls.
- A higher percentage of children with protracted bronchitis (63%) had persistent cough at day 14 versus asthma (24%) and control groups (26%).
Conclusions:
- Protracted bronchitis is associated with the most severe ARI symptoms in children.
- Children with protracted bronchitis exhibit greater respiratory morbidity at 14 days post-illness onset compared to asthmatic and healthy children.
Aim:
Acute respiratory infections (ARI) are common in children, and symptoms range from days to weeks. The aim of this study was to determine if children with asthma have more severe ARI episodes compared with children with protracted bronchitis and controls.
Methods:
Parents prospectively scored their child's next ARI using the Canadian acute respiratory illness and flu scale (CARIFS) and a validated cough diary (on days 1-7, 10 and 14 of illness). Children were age- and season-matched.
Results:
On days 10 and 14 of illness, children with protracted bronchitis had significantly higher median CARIFS when compared with children with asthma and healthy controls. On day 14, the median CARIFS were: asthma = 4.1 (interquartile range (IQR) 4.0), protracted bronchitis = 19.6 (IQR 25.8) and controls = 4.1 (IQR 5.25). The median cough score was significantly different between groups on days 1, 7, 10 and 14 (P < 0.001). A significantly higher proportion of children with protracted bronchitis (63%) were still coughing at day 14 in comparison with children with asthma (24%) and healthy controls (26%).
Conclusion:
Children with protracted bronchitis had the most severe ARI symptoms and higher percentage of respiratory morbidity at day 14 in comparison with children with asthma and healthy controls.
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