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Using Microfluidics and Fluorescence Microscopy to Study the Assembly Dynamics of Single Actin Filaments and Bundles
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{beta}CaMKII regulates actin assembly and structure.

Hugo Sanabria1, Matthew T Swulius, Steven J Kolodziej

  • 1Departments of Neurobiology and Anatomy and Pathology and Laboratory Medicine, University of Texas Health Science Center, Houston, Texas 77030, USA.

The Journal of Biological Chemistry
|February 12, 2009
PubMed
Summary

Calcium-Calmodulin-dependent protein kinase II (CaMKII) beta isoform binds and bundles actin filaments. This protein kinase also inhibits actin polymerization, impacting synaptic structure and dynamics.

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