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In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones
11:36

In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones

Published on: July 25, 2019

Nucleolar structure and function are regulated by the deubiquitylating enzyme USP36.

Akinori Endo1, Masaki Matsumoto, Toshifumi Inada

  • 1Department of Biological Sciences, Tokyo Institute of Technology, Yokohama 226-8501, Japan.

Journal of Cell Science
|February 12, 2009
PubMed
Summary

USP36, a deubiquitylating enzyme, regulates nucleolar activity by stabilizing key proteins like nucleophosmin/B23. Its depletion impairs ribosome biogenesis and cell proliferation.

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