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Updated: Jun 25, 2026

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Published on: March 13, 2018

Chikungunya: an overview.

A B Sudeep¹, D Parashar

¹National Institute of Virology, 20-A, Dr Ambedkar Road, Pune 411 001, India. sudeepmcc@yahoo.co.in

Journal of Biosciences

|February 12, 2009

Summary

Chikungunya (CHIK) is a mosquito-borne illness characterized by fever and severe joint pain. Recent outbreaks reveal unusual complications and prolonged morbidity, impacting public health significantly.

Area of Science:

Virology
Epidemiology
Public Health

Background:

Chikungunya (CHIK) is a debilitating mosquito-borne viral disease caused by the CHIK virus (family Togaviridae).
Characterized by abrupt high fever, rash, and severe arthralgia, CHIK outbreaks have occurred globally since its first report in Tanzania in 1952-53.
The virus has three genotypes (Asian, West African, East Central South African), each associated with regional epidemics.

Observation:

India experienced significant CHIK outbreaks in the 1960s-70s and a major resurgence after 32 years, affecting over 1.4 million people.
The recent epidemic presented unusual clinico-pathological complications, including CHIK-associated mortality and mother-to-child transmission.
Prolonged high morbidity, particularly severe arthralgia lasting months, resulted in significant mental and physical debilitation.

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Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Published on: March 13, 2018

Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus

Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus

Published on: May 31, 2020

Findings:

The review details the general aspects of CHIK virus and its disease manifestations.
It highlights specific clinico-pathological features observed during the recent large-scale Indian outbreak.
Analysis of viral genotypes and their epidemiological spread is discussed in relation to outbreak patterns.

Implications:

Understanding CHIK's diverse clinical presentations and complications is crucial for effective disease management.
The findings underscore the need for robust public health surveillance and control strategies for mosquito-borne viral diseases.
Further research into CHIK pathogenesis and long-term sequelae is warranted to mitigate its impact on affected populations.