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Related Concept Videos

Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...
Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
American Trypanosomiasis01:22

American Trypanosomiasis

Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
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Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
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Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

Brucellosis in India - a review.

Basappa G Mantur1, Satish K Amarnath

  • 1Department of Microbiology, Belgaum Institute of Medical Sciences, District Hospital Campus, Belgaum 590 001, India. drbgmantur@rediffmail.com

Journal of Biosciences
|February 12, 2009
PubMed
Summary

Brucellosis, a neglected zoonotic disease, remains a significant public health issue, especially in India. Enhanced surveillance, diagnostics, and public awareness are crucial for controlling this re-emerging infection.

Area of Science:

  • * Zoonotic diseases
  • * Public health
  • * Epidemiology

Background:

  • * Brucellosis is a re-emerging zoonotic disease with global distribution.
  • * It poses a significant, often neglected, public health challenge in developing nations like India.
  • * Brucella melitensis is the predominant species globally, with cattle as a key reservoir.

Purpose of the Study:

  • * To review the discovery, isolation, and diagnosis of Brucellosis.
  • * To analyze the epidemiology and control measures in the Indian context.
  • * To highlight challenges and needs for Brucellosis management.

Main Methods:

  • * Comprehensive review of global literature on Brucellosis.
  • * Analysis of epidemiological data and diagnostic challenges.

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Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells
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Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells

Published on: August 5, 2016

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Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
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Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

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Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells
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Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells

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  • * Examination of control strategies in India.
  • Main Results:

    • * Brucellosis is common but often overlooked in India, with Brucella melitensis being prevalent.
    • * Wild animals and non-terrestrial sources present epidemiological complexities.
    • * Routine surveillance and family screening are vital for accurate magnitude assessment.
    • * International travel complicates diagnosis in non-endemic regions.

    Conclusions:

    • * Urgent need for advanced diagnostic tools and alternative treatments for Brucellosis.
    • * Human vaccines are unavailable; prevention relies on public awareness and safe livestock practices.
    • * Collaboration between health and veterinary sectors is essential for effective control.