Related Experiment Video
Updated: Jun 25, 2026

Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice
Published on: September 25, 2019
The treatment of chronic hepatitis B: Focus on adefovir-like antivirals
1Medizinische Klinik und Poliklinik II, Universität Leipzig, Germany. Hans.Tillmann@duke.edu
Abstract:
SEVERAL OPTIONS FOR THE TREATMENT OF HEPATITIS B HAVE BEEN LICENSED IN THE LAST YEARS: interferon, pegylated interferon, lamivudine, adefovir, entecavir, and telbivudine. In addition tenofovir has been licensed in the EU and is expected to be licensed in the USA in 2008. The antivirals can be divided into "lamivudine-like" and "adefovir-like", which clinically differ in their capacity to induce "YMDD" mutants, which are the hallmark of lamivudine resistance. The differing resistance profile makes them good combination partners, even in the absence of synergy in antiviral potency.
Related Concept Videos
Hepatitis
Antiviral Nucleoside Inhibitors
Inhibitors of Viral Protein Synthesis
Viral Hepatitis I: Introduction
Retrovirus Life Cycles
Viruses with RNA Genomes
