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Updated: Jun 25, 2026
05:12
Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
Published on: June 23, 2023
[Association between ethanol intake and ischemic heart disease].
Giampaolo Niccoli1, Marco Bacà, Nicola Cosentino
1Istituto di Cardiologia, Università Cattolica del Sacro Cuore, Roma. gniccoli73@hotmail.it
Recenti Progressi in Medicina
|February 13, 2009
Summary
Moderate alcohol consumption may protect the heart, but heavy drinking increases cardiovascular risks. This review examines ethanol
Area of Science:
- Cardiovascular Science
- Toxicology
- Epidemiology
Context:
- Alcohol (ethanol) consumption is widespread globally.
- Ethanol's health effects are dose-dependent, exhibiting both beneficial and detrimental impacts.
- Existing research indicates J- or U-shaped relationships between alcohol intake and various health issues.
Purpose:
- To review epidemiological and experimental evidence on ethanol's effects in ischemic heart disease.
- To elucidate the dual role of ethanol in cardiovascular health and disease.
- To highlight recent findings on moderate versus heavy alcohol consumption's impact.
Summary:
- Moderate ethanol intake is linked to cardioprotective effects, potentially via improved inflammation, lipid profiles, and coagulation.
- Heavy or binge drinking is associated with increased cardiovascular events and mortality.
- High ethanol doses may impair ischemic preconditioning, a protective mechanism against heart attacks.
Impact:
- Provides a comprehensive overview of ethanol's complex relationship with ischemic heart disease.
- Informs public health guidelines regarding alcohol consumption and cardiovascular risk.
- Highlights the need for nuanced understanding of alcohol's effects beyond simple categorization.
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