[Cardiovascular disease and venous thromboembolism. Different disorders or possible intriguing association?]

Walter Ageno1, Francesco Dentali, Erica Romualdi

  • 1Dipartimento di Medicina Clinica, Università degli Studi dell'Insubria, Varese.

Insights

Venous thromboembolism (VTE) and cardiovascular disease (CVD) may be linked. This review explores shared risk factors and the higher risk of cardiovascular events in individuals with a history of VTE.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Epidemiology

Background:

  • Venous thromboembolism (VTE) and cardiovascular disease (CVD) are typically considered distinct conditions.
  • Emerging clinical evidence suggests a potential relationship between VTE and CVD.
  • Understanding this association is crucial for comprehensive patient care.

Purpose of the Study:

  • To review existing literature on the association between VTE and CVD.
  • To identify shared risk factors contributing to both conditions.
  • To examine the increased incidence of cardiovascular events following a VTE episode.

Main Methods:

  • Systematic literature search of relevant studies.
  • Narrative review of published evidence.
  • Analysis of shared risk factors and cardiovascular outcomes.

Main Results:

  • Evidence supports a significant relationship between VTE and CVD.
  • Common risk factors include age, obesity, hypertension, and smoking.
  • Patients with a history of VTE exhibit a higher incidence of subsequent cardiovascular events.

Conclusions:

  • VTE and CVD share common pathophysiological pathways and risk factors.
  • A history of VTE may indicate an increased predisposition to cardiovascular disease.
  • Further research is warranted to elucidate the underlying mechanisms and optimize management strategies.

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