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Related Concept Videos

Signs of Puberty01:27

Signs of Puberty

Puberty is a critical phase, typically beginning between the ages of 8 and 13 in girls and 9 and 14 in boys, though timing can vary based on genetics, environmental factors, and overall health. This period is characterized by the development of secondary sexual characteristics and the attainment of reproductive potential. Endocrine changes underpin puberty, with hormonal surges of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) instigated by Gonadotropin-Releasing Hormone (GnRH)...
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In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...
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Related Experiment Video

Updated: Jun 25, 2026

Determination of Reproductive Competence by Confirming Pubertal Onset and Performing a Fertility Assay in Mice and Rats
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Published on: October 13, 2018

Pubertal development of Turkish children.

Serap Semiz1, Funda Kurt, Devrim Tanil Kurt

  • 1Division of Pediatric Endocrinology, Department of Pediatrics, Pamukkale University Faculty of Medicine, Denizli, Turkey. drssemiz@yahoo.com

Journal of Pediatric Endocrinology & Metabolism : JPEM
|February 13, 2009
PubMed
Summary

This study tracked pubertal development in Turkish children, finding that girls initiate puberty earlier than in other global populations. Boys

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Area of Science:

  • Pediatric Endocrinology
  • Human Growth and Development
  • Public Health

Background:

  • Understanding typical pubertal development is crucial for identifying deviations and ensuring child health.
  • Secular trends in pubertal timing can reflect changes in environmental and socioeconomic factors.
  • Establishing normative data for specific populations is essential for accurate clinical assessment.

Purpose of the Study:

  • To document the current status of pubertal development in a contemporary cohort of Turkish school children.
  • To identify potential secular trends by comparing findings with historical data.
  • To provide reference standards for sexual maturation in Turkish youth.

Main Methods:

  • A cross-sectional study involving 1,562 girls and 1,749 boys aged 6-16.5 years.
  • Assessment of anthropometric measures (height, weight, BMI) and pubertal stages using Tanner criteria.
  • Measurement of testicular volume in boys and recording of menarcheal age in girls.

Main Results:

  • Mean age at menarche was 12.41 years; overweight/obese girls experienced earlier menarche.
  • Detailed mean ages for various Tanner stages (breast and pubic hair) were established for both sexes.
  • Boys' pubertal onset was comparable to international norms, while girls' onset appeared earlier.

Conclusions:

  • This study establishes current reference ranges for pubertal maturation in Turkish children.
  • Turkish girls exhibit an earlier onset of puberty compared to international benchmarks.
  • Further research is warranted to explore the factors contributing to these observed trends.