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Related Concept Videos

Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...
Peptide Identification Using Tandem Mass Spectrometry01:33

Peptide Identification Using Tandem Mass Spectrometry

Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...
Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
MALDI-TOF Mass Spectrometry01:19

MALDI-TOF Mass Spectrometry

Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.Matrix-assisted laser desorption ionization (MALDI) is a commonly...
Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique helps...

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Proteomics: technology development and applications.

S Patrick Walton1, Arul Jayaraman

  • 1Department of Chemical Engineering and Materials Science, Michigan State University, East Lansing, MI 48824-1226, USA. spwalton@egr.msu.edu

Expert Review of Proteomics
|February 13, 2009
PubMed
Summary
This summary is machine-generated.

Proteomics technology is a growing field in chemical engineering, with significant applications in biomedical and biochemical engineering. Presentations at the 2008 AIChE meeting highlighted the value and developing role of proteomics in biological and clinical analyses.

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Area of Science:

  • Chemical Engineering
  • Biomedical Engineering
  • Biochemical Engineering
  • Proteomics

Background:

  • The 2008 American Institute of Chemical Engineers (AIChE) Annual Meeting showcased emerging trends in chemical engineering.
  • Biomedical and biochemical engineering are expanding areas within the discipline.
  • Proteomics is gaining recognition for its technological development and applications.

Framework:

  • The AIChE Annual Meeting, held concurrently with the American Electrophoresis Society Annual Meeting, provided a platform for discussing proteomics.
  • Presentations focused on the value and applicability of proteomics.
  • Academic and industrial perspectives on proteomics were shared.

Implementation:

  • Technological advancements in proteomics were a key topic.
  • The application of proteomics in various fields was demonstrated.
  • The integration of proteomics into biological and clinical analyses was explored.

Implications:

  • Proteomics is poised to play an increasingly important role in chemical engineering, particularly in biomedical and biochemical applications.
  • The development of proteomic technologies offers new avenues for biological and clinical research.
  • Collaboration between chemical engineers and the American Electrophoresis Society is advancing the field of proteomics.