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Risk factors for urinary tract infection in children: a population-based study of 2856 children
Premala Sureshkumar1, Mike Jones, Robert G Cumming
1Centre for Kidney Research, NHMRC Centre for Clinical Research Excellence, The Children's Hospital at Westmead, Australia. premalas@chw.edu.au
Insights
Urinary tract infections (UTIs) in children are linked to kidney abnormalities, daytime incontinence, and encopresis. Addressing these issues, especially incontinence in boys, may help prevent UTIs.
Area of Science:
- Pediatrics
- Urology
- Infectious Diseases
Background:
- Urinary tract infections (UTIs) are common in children, with various risk factors contributing to their development.
- Accurate identification of these risk factors is crucial for effective prevention strategies.
Purpose of the Study:
- To identify key risk factors associated with urinary tract infections (UTIs) in elementary school-aged children.
- To provide data for developing targeted preventative measures against childhood UTIs.
Main Methods:
- A cross-sectional study surveyed parents of 2856 elementary school children using a validated questionnaire.
- Urinary tract infection (UTI) status was confirmed through parental reports cross-referenced with microbiological data.
Main Results:
- A history of structural kidney abnormalities, daytime incontinence, female gender, and encopresis were independently associated with UTIs.
- Parents over-reported UTI cases by approximately threefold compared to verified diagnoses.
- Daytime incontinence posed a higher risk for boys, while kidney problems were more prevalent in older children.
Conclusions:
- Parental reporting of UTIs is significantly higher than verified cases.
- Treating daytime urinary incontinence and encopresis may be effective in preventing UTIs in children, particularly boys.
Aim:
To identify risk factors for urinary tract infection (UTI) in children to inform the development of preventative strategies.
Method:
A validated questionnaire covering demographic factors, perinatal, developmental, bowel and urinary history was sent to a cross-sectional sample of parents of elementary school children randomly selected from the first 4 years of school. UTI was ascertained by parental report, verified by cross-referencing with microbiological reports for all positive cases and 50 randomly selected negative cases.
Results:
Parents of 2856 children (mean age 7.3 years, range 4.8-12.8 years) responded. A total of 3.6% of children had a bacteriologically verified UTI, compared with 12.6% by parental report alone. Multivariate polychotomous logistic regression showed that a history of structural kidney abnormalities (odds ratio (OR) 15.7, 95% confidence interval 8.1-30.4), daytime incontinence (OR 2.6, 1.6-4.5), female gender (OR 2.4, 1.5-3.8), and encopresis (OR 1.9, 1.1-3.4) were independently associated with UTI. Daytime incontinence increased risk more in boys (8.3% vs. 1.2%) than girls (8.1% vs. 4.6%), and kidney problems increased risk in older compared with younger children (29% vs. 2% in > or =8 year olds, 0% vs. 4% in 4-6 year olds).
Conclusions:
Parents over-report UTI by about threefold. Effective treatment of daytime urinary incontinence and encopresis may prevent UTI in children, especially boys.
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