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Four-country surveillance of intestinal intussusception and diarrhoea in children

Shally Awasthi1, Girdhar G Agarwal, Vikas Mishra

  • 1Department of Paediatrics, King George Medical University, Lucknow, India. sawasthi@sancharnet.in

Journal of Paediatrics and Child Health
|February 13, 2009
PubMed

Insights

Intussusception cases in developing countries showed no seasonal pattern. Establishing surveillance networks is feasible and crucial before rotavirus vaccine introduction.

Area of Science:

  • Pediatric Gastroenterology
  • Infectious Disease Epidemiology
  • Public Health Surveillance

Background:

  • Baseline epidemiology of intussusception is needed due to potential rotavirus vaccine reintroduction.
  • Developing countries require robust data on intussusception and diarrheal diseases.

Purpose of the Study:

  • To assess the seasonal trends of intussusception and dehydrating acute watery diarrhea admissions in children.
  • To evaluate the feasibility of establishing an intussusception surveillance network in developing countries.

Main Methods:

  • Prospective surveillance study conducted across hospital sites in India, Brazil, Egypt, and Kenya.
  • Network of hospitals with surgical facilities monitored intussusception cases within a reference population of 1-2 million.
  • One large hospital per site also recruited admitted cases of acute watery diarrhea.

Main Results:

  • 173 intussusception and 2346 diarrhea cases were recruited between April 2004 and March 2006.
  • Intussusception cases exhibited no apparent seasonality; 61.3% were in infants under 1 year.
  • Diarrhea cases peaked in March, with high antibiotic use (83.1%) and 0.8% hospital mortality.

Conclusions:

  • Intussusception demonstrated no seasonal trend in the participating developing countries.
  • Establishing a surveillance network for intussusception in these regions is feasible.
  • Population-based data is essential before and after rotavirus vaccine introduction.
Abstract

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