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Related Concept Videos

Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Type I Diabetes III: Clinical Manifestations01:19

Type I Diabetes III: Clinical Manifestations

Type 1 diabetes mellitus typically presents with rapid-onset symptoms due to the body’s inability to utilize glucose in the absence of insulin. Since insulin is required for glucose uptake into cells, its deficiency leads to hyperglycemia and cellular energy deprivation, resulting in characteristic clinical features.Polyuria and PolydipsiaOne of the earliest, most prominent symptoms is polyuria (excessive urination). When blood glucose concentrations rise above the renal threshold, the kidneys...
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis01:25

Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis

Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated hypertension...
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Diabetic Nephropathy01:28

Diabetic Nephropathy

Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...

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Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
04:22

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Erectile dysfunction in diabetes mellitus.

Lasantha S Malavige1, Jonathan C Levy

  • 1Department of Clinical Medicine, University of Oxford, Nuffield, Oxford OX3 7LJ, UK. lasantha.malavige@ocdem.ox.ac.uk

The Journal of Sexual Medicine
|February 13, 2009
PubMed
Summary
This summary is machine-generated.

Erectile dysfunction (ED) in type 2 diabetes is multifactorial and distinct from non-diabetic ED. Management requires a holistic approach addressing glycaemic control, comorbidities, lifestyle, and specific ED treatments.

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Last Updated: Jun 25, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
04:22

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Area of Science:

  • Endocrinology
  • Urology
  • Public Health

Background:

  • Type 2 diabetes is a global epidemic with increasing rates in younger populations.
  • Erectile dysfunction (ED) is a frequent and distressing complication of diabetes, with unique pathophysiology and management challenges compared to non-diabetic ED.

Purpose of the Study:

  • To present an updated review on the epidemiology, risk factors, pathophysiology, and management strategies for diabetic ED.

Main Methods:

  • Literature search conducted using Medline and Embase databases.
  • Inclusion of relevant textbook information for a comprehensive review.

Main Results:

  • Prevalence of ED in diabetic men varies widely (35%-90%) due to methodological and population differences.
  • Risk factors include age, diabetes duration, poor glycaemic control, hypertension, hyperlipidemia, sedentary lifestyle, smoking, and other diabetic complications.
  • Diabetic ED is multifactorial, more severe, and treatment-resistant; management involves optimized glycaemic control, comorbidity management, lifestyle changes, and potentially psychosexual counseling, hypogonadism treatment, PDE5 inhibitors, or alternative therapies for non-responders.

Conclusions:

  • The etiology of diabetic ED is complex and multifactorial, though the precise contribution of each factor requires further clarification.
  • A comprehensive, holistic management strategy is essential for addressing diabetic ED effectively.