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Related Concept Videos

Psychosis and Antipsychotic Drugs: Overview01:28

Psychosis and Antipsychotic Drugs: Overview

The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic symptoms in all...
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Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation. For...
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Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those diagnosed.
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Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
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Bipolar Disorder01:30

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Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
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Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
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Published on: August 18, 2020

[Feeling for affective psychosis].

Lars Vedel Kessing1

  • 1Psykiatrisk Afdeling, Rigshospitalet, DK-2100 København Ø. lars.kessing@rh.dk

Ugeskrift for Laeger
|February 13, 2009
PubMed
Summary
This summary is machine-generated.

This research explores the causes of depression and mania, identifying potential biomarkers like neuroticism and altered brain activity. These findings may lead to improved diagnostic and treatment strategies for mood disorders.

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Genetics

Context:

  • Depression and mania pathogenesis involve complex gene-environment interactions.
  • Deep brain stimulation can acutely induce mood disturbances in subthalamic areas.
  • Current understanding of mood disorder etiology is evolving.

Purpose:

  • To present novel research findings on the pathogenesis of depression and mania.
  • To discuss future perspectives in the diagnosis and treatment of these conditions.
  • To identify potential biomarkers for mood disorders.

Summary:

  • Research suggests biomarkers for depression and mania include neuroticism, abnormal DEX-CRH test responses, altered serotonin 2A binding, and impaired executive function.
  • These potential biomarkers arise from ongoing studies investigating the interplay of genetic and environmental factors.
  • Mood disorders may be triggered by specific neurobiological mechanisms, including those influenced by deep brain stimulation.

Impact:

  • Identified biomarkers could significantly enhance the accuracy of diagnosing depression and mania.
  • Future treatments for mood disorders may be personalized based on these emerging biomarkers.
  • This research contributes to a deeper understanding of the neurobiological underpinnings of mood disorders.