Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dose escalation in pediatric pelvic Ewing's Sarcoma: Insights from a national treatment planning exercise.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)·2025
Same author

Assessment and Prediction of Salivary Gland Function After Head and Neck Radiotherapy: A Systematic Review.

Cancer medicine·2024
Same author

Feasibility and Safety of the "One-Week Breast Radiation Therapy" Program.

Clinical oncology (Royal College of Radiologists (Great Britain))·2024
Same author

[Does radiation therapy for prostate cancer increase the risk of second cancers?]

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2024
Same author

[Informed consent in radiotherapy care].

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2024
Same author

Indication and perspectives of radiation therapy in the setting of de-novo metastatic prostate cancer.

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2023

Related Experiment Video

Updated: Jun 25, 2026

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
10:48

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

[Image-guided radiotherapy: rational, modalities and results].

R de Crevoisier1, G Louvel, G Cazoulat

  • 1Département de radiothérapie, centre Eugène-Marquis, avenue Bataille-Flandres-Dunkerque, 35042 Rennes, France. r.de-crevoisier@rennes.fnclcc.fr

Bulletin Du Cancer
|February 13, 2009
PubMed
Summary

Image-Guided Radiotherapy (IGRT) improves cancer treatment accuracy by accounting for organ motion and deformation during radiation delivery. This technique shows promising results with minimal toxicity, enhancing tumor targeting and patient outcomes.

More Related Videos

Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
07:57

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

Published on: March 24, 2022

Related Experiment Videos

Last Updated: Jun 25, 2026

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
10:48

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
07:57

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

Published on: March 24, 2022

Area of Science:

  • Oncology
  • Medical Physics
  • Radiotherapy Technology

Context:

  • Cancer treatment requires precise targeting to minimize damage to healthy tissues.
  • Anatomical variations during treatment, such as organ motion and deformation, pose a significant challenge to radiotherapy accuracy.
  • Advances in functional imaging and intensity-modulated radiotherapy necessitate adaptive strategies for improved treatment delivery.

Purpose:

  • To review the principles, technologies, and clinical applications of Image-Guided Radiotherapy (IGRT).
  • To highlight how IGRT addresses inter- and intrafraction anatomical variations for enhanced treatment accuracy.
  • To discuss the role of IGRT in optimizing tumor definition and dose distribution.

Summary:

  • IGRT utilizes real-time imaging (e.g., kV/MV Cone Beam CT, CyberKnife, TomoTherapy) to visualize tumor position during radiation delivery.
  • Treatment adjustments, including table repositioning or replanning, are made if the tumor deviates from its planned location.
  • IGRT facilitates a more accurate definition of the Planning Target Volume (PTV) and enables adaptive radiotherapy strategies.

Impact:

  • IGRT has demonstrated promising clinical outcomes, including reports of minimal acute toxicity.
  • The technique supports the integration of advanced imaging and dose calculation methods for personalized cancer care.
  • Robust quality control is essential for the safe and effective clinical evaluation of IGRT's benefits.