Related Experiment Video
Updated: Jun 25, 2026

11:20
Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
Published on: June 14, 2021
25-Gauge vitrectomy for paediatric vitreoretinal conditions
C R Gonzales1, S Singh, S D Schwartz
1Retina and Vitreous Center, Ashland, Oregon, USA. cgonzales@retinaandvitreous.com
The British Journal of Ophthalmology
|February 13, 2009
Summary
This study shows that 25-gauge vitrectomy is a feasible and safe surgical option for pediatric vitreoretinal conditions. A modified sutured technique is recommended for infants to prevent postoperative hypotony.
Area of Science:
- Ophthalmology
- Pediatric Surgery
- Retinal Surgery
Background:
- Pediatric vitreoretinal surgery presents unique challenges due to the small size of the eye.
- Minimally invasive techniques are desirable to reduce complications in pediatric patients.
Purpose of the Study:
- To assess the feasibility and safety of 25-gauge vitrectomy in children for various vitreoretinal conditions.
- To compare outcomes between standard and modified surgical approaches in different age groups.
Main Methods:
- Retrospective analysis of 56 eyes from 49 children (≤18 years) undergoing 25-gauge vitrectomy over 5 years.
- Two techniques were employed: a modified sutured approach for infants (<1 year) and a transconjunctival approach for older children.
- Data on intraoperative and postoperative complications were collected and analyzed.
Main Results:
- No cases of endophthalmitis, wound leaks, or hypotony requiring treatment were reported.
- Minor intraoperative events included conversions to 20-gauge and bleeding.
- Postoperative complications included cataract, retinal detachment, and vitreous hemorrhage, often in eyes with complex pathology.
Conclusions:
- 25-gauge vitrectomy is a viable and safe technique for pediatric vitreoretinal surgery, offering good access to small ocular spaces.
- A modified sutured technique is recommended for infants to mitigate the risk of postoperative hypotony.

