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Updated: Jun 25, 2026
Fluorescence detection methods for microfluidic droplet platforms
Published on: December 10, 2011
Individual nanoparticle detection in liquids by thermal lens microscopy and improvement of detection efficiency using
Nobuhiro Seta1, Kazuma Mawatari, Takehiko Kitamori
1Department of Applied Chemistry, School of Engineering, The University of Tokyo, Japan.
Abstract:
Nanoparticles are a key material in nanoscience and nanotechnology due to their unique physicochemical properties, so an analytical method is increasingly required. In the present research, we developed a method for individual nanoparticle detection by thermal lens microscopy and microfluidic chips. Pulsed signals were clearly observed, as nanoparticles were passing through the detection volume. The scale of the microfluidic channel was reduced from 100 to 1 microm to improve the detection efficiency. As a result, a detection efficiency of 100% was demonstrated.
