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Updated: Jul 28, 2026

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice
Published on: August 4, 2011
[Difficulties and errors in the diagnosis of retinoblastoma]
H Zygulska-Machowa1, Z Maciejewski, M Sadowska
1Kliniki Okulistycznej AM w Krakowie, Kraków, Poland.
Abstract:
The authors analyzed the results of the clinical and histopathological examination of the eyes of 283 children with an initially diagnosed intraocular tumor. In 32 cases (11.4 p.c.) there was no retinoblastoma but a congenital retinal dysplasia, vitreal dysplasia, Leber-Coats disease, chronic inflammatory conditions, or retinopathy of prematurity. Three eyes exhibited rare forms of intraocular tumors. In 4 cases among 283 (1.4 p.c.) the diagnosis was erroneously negative. One suspected the Leber-Coats, Hippel-Lindau disease or posterior uveitis. The pathological examination revealed the presence of retinoblastoma.
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