Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A bone biopsy procedure for neonatal pigs.

D J Bobilya1, M G Maurizi, T L Veum

  • 1Department of Animal Sciences, College of Agriculture, University of Missouri, Columbia.

Laboratory Animals
|July 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

New and Interesting Fungi. 3.

Fungal systematics and evolution·2020
Same author

Twin- or single-screw extrusion of raw soybeans and preconditioned soybean meal and corn as individual ingredients or as corn-soybean product blends in diets for weanling swine.

Journal of animal science·2017
Same author

Hulled and hull-less barley grains with the genetic trait for low-phytic acid increased the apparent total-tract digestibility of phosphorus and calcium in diets for young swine.

Journal of animal science·2016
Same author

Methane digester effluent from swine excreta as a nutrient and water source for growing and finishing swine.

Journal of animal science·2015
Same author

Relative availability of zinc in ground beef and soybean protein for young swine compared with zinc carbonate as the standard.

Journal of animal science·2014
Same author

Effects of cecal oxytetracycline infusion, and dietary avidin and biotin supplementation on the biotin status of nongravid gilts.

Journal of animal science·2012

Researchers developed a minimally invasive bone biopsy technique in neonatal pigs. This surgical method effectively obtains bone samples for analysis and shows promise for pediatric applications.

Area of Science:

  • Veterinary Surgery
  • Pediatric Bone Biopsy
  • Animal Models in Research

Background:

  • Developing effective bone biopsy techniques is crucial for diagnosing conditions in small patients.
  • Existing methods may be too invasive for neonatal or pediatric subjects.
  • Neonatal pigs offer a suitable anatomical model for developing human infant procedures.

Purpose of the Study:

  • To establish a novel surgical biopsy procedure for obtaining iliac bone tissue in neonatal pigs.
  • To assess the feasibility of this technique for various analyses, including mineral content.
  • To evaluate the safety and repeatability of the procedure in a young animal model.

Main Methods:

  • A surgical punch biopsy technique using a scalpel and Craig Biopsy Trephine was employed on neonatal pigs under general anesthesia.

Related Experiment Videos

  • Bone core samples of 5-15 mm length and 2-3 mm diameter were extracted from the ilium.
  • Repeated biopsies were performed on each pig weekly for five weeks to assess surgical trauma and recovery.

    • Main Results:

    • The biopsy procedure successfully yielded bone samples suitable for mineral (calcium, zinc) analysis, with potential for histological and biochemical studies.
    • Average dry weight of samples was 34.4 mg.
    • Minimal surgical trauma was observed, allowing for repeated biopsies without adverse effects.

    Conclusions:

    • The developed surgical biopsy technique is effective and safe for obtaining iliac bone samples in neonatal pigs.
    • This method has significant potential for application in infant and pediatric bone tissue sampling and analysis.
    • The procedure's minimal invasiveness supports its use in longitudinal studies or repeated sampling in small animal models.