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Related Concept Videos

Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
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Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Viral Meningitis01:18

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Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
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Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
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[Pasteurella multocida bacteremic meningitis].

R Soloaga1, N Carrión, J Pidone

  • 1Servicio de Microbiología del Hospital Naval Cirujano Mayor Dr. Pedro Mallo, Patricias Argentinas 351 (1405) Ciudad Autónoma de Buenos Aires, Argentina. rnsoloaga@yahoo.com

Revista Argentina De Microbiologia
|February 14, 2009
PubMed
Summary
This summary is machine-generated.

This case report details a rare instance of Pasteurella multocida bacteremic meningitis in an elderly woman with cat exposure. The identified P. multocida strain showed susceptibility to common antibiotics.

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Area of Science:

  • Infectious Diseases
  • Microbiology
  • Neurology

Background:

  • Pasteurella multocida commonly causes infections following animal bites or scratches.
  • Oropharyngeal flora from domestic animals frequently co-infects humans.

Observation:

  • An 86-year-old woman with extensive cat contact developed bacteremic meningitis.
  • No overt skin or soft tissue infection was noted prior to meningitis diagnosis.

Findings:

  • Blood and cerebrospinal fluid cultures confirmed Pasteurella multocida.
  • Microbial identification was performed using API 20NE, API 20E, and Vitek 1 systems.
  • The P. multocida isolate was susceptible to penicillin, cefotaxime, levofloxacin, and tetracyclines.

Implications:

  • Highlights potential for P. multocida meningitis from non-bite/scratch animal contact.
  • Suggests possible routes of infection include undetected mild skin infections or nasopharyngeal colonization.
  • Informs antibiotic selection for P. multocida meningitis based on susceptibility patterns.