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Prevalence of celiac disease in north Indian children

Malobika Bhattacharya1, A P Dubey, N B Mathur

  • 1Department of Pediatrics, Maulana Azad Medical College and Lok Nayak Hospital, Delhi 110 002, India.

Indian Pediatrics
|February 14, 2009
PubMed

Insights

Celiac disease (CD) prevalence in North Indian children is 1%, based on screening 400 children aged 6 months to 12 years. This study provides crucial data on pediatric CD in the region.

Area of Science:

  • Pediatric Gastroenterology
  • Immunology
  • Public Health

Background:

  • Celiac disease (CD) is increasingly diagnosed in North India's wheat-consuming population.
  • Limited data exists on the prevalence of pediatric CD in this region due to scarce screening studies.

Purpose of the Study:

  • To determine the prevalence of celiac disease in children aged 6 months to 12 years.
  • To screen children attending a tertiary care hospital in North India for CD.

Main Methods:

  • Screening of 400 children using antitissue transglutaminase (tTG) antibodies.
  • Endoscopic duodenal biopsy for tTG-positive subjects.
  • Diagnosis based on modified ESPGHAN criteria.

Main Results:

  • Four patients were diagnosed with celiac disease.
  • The overall prevalence of CD in the study population was 1%.

Conclusions:

  • The study establishes a 1% prevalence of pediatric celiac disease in North India.
  • Findings align with Western serological screening studies, highlighting the need for regional awareness and screening.

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