Related Experiment Video
Updated: Jun 25, 2026
07:44
In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
Repeatability of corneal thickness measured using an Oculus Pentacam
Marco A Miranda1, Hema Radhakrishnan, Clare O'Donnell
1Faculty of Life Sciences, The University of Manchester, United Kingdom. marco.miranda@postgrad.manchester.ac.uk
Summary
The Oculus Pentacam demonstrates repeatable corneal thickness measurements over time, confirming its reliability for clinical use. This study highlights consistent results within seconds, after one hour, and one week.
Area of Science:
- Ophthalmology
- Medical Imaging
- Corneal Physiology
Background:
- Accurate corneal thickness measurement is crucial for diagnosing and managing various ocular conditions.
- The Oculus Pentacam is a widely used device for anterior segment analysis, including pachymetry.
Purpose of the Study:
- To assess the repeatability of corneal thickness measurements using the Oculus Pentacam.
- To evaluate measurement consistency at different time intervals: immediately, 1 hour, and 1 week post-initial measurement.
Main Methods:
- Corneal thickness (apical and peripheral) was measured in 23 healthy subjects using the Oculus Pentacam.
- Three consecutive measurements were taken per session by the same observer across three sessions.
- Measurements were performed immediately after a blink to standardize conditions.
Main Results:
- Corneal thickness measurements showed good repeatability across all time points (within seconds, 1 hour, 1 week).
- Mean central corneal thickness values were consistent with published literature.
- Intraobserver reproducibility decreased towards the corneal periphery, with wider confidence limits observed.
Conclusions:
- The Oculus Pentacam provides repeatable corneal thickness measurements, supporting its use in clinical practice.
- The device is reliable for assessing corneal thickness at short intervals and up to one week.
