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Updated: Jun 25, 2026

MS2-Affinity Purification Coupled with RNA Sequencing in Gram-Positive Bacteria
Published on: February 23, 2021
Specific features of 5S rRNA structure - its interactions with macromolecules and possible functions
A V Smirnov1, N S Entelis, I A Krasheninnikov
1Faculty of Biology, Lomonosov Moscow State University, Moscow, 119991, Russia. skard1@yandex.ru
Abstract:
Small non-coding RNAs are today a topic of great interest for molecular biologists because they can be regarded as relicts of a hypothetical "RNA world" which, apparently, preceded the modern stage of organic evolution on Earth. The small molecule of 5S rRNA (approximately 120 nucleotides) is a component of large ribosomal subunits of all living beings (5S rRNAs are not found only in mitoribosomes of fungi and metazoans). This molecule interacts with various protein factors and 23S (28S) rRNA. This review contains the accumulated data to date concerning 5S rRNA structure, interactions with other biological macromolecules, intracellular traffic, and functions in the cell.
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