Chemical tools selectively target components of the PKA system

Daniela Bertinetti1, Sonja Schweinsberg1, Susanne E Hanke1

  • 1Department of Biochemistry, University of Kassel, Heinrich-Plett-Str. 40, 34132 Kassel, Germany.

BMC Chemical Biology
|February 17, 2009
PubMed
Summary

Researchers developed novel cyclic adenosine monophosphate (cAMP) analogs for improved purification of cAMP binding proteins. Sp-8-AEA-cAMPS demonstrated superior enrichment and mild elution for protein kinase A (PKA) purification.

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