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Neovascular glaucoma, endophthalmitis and evisceration
1Department of Ophthalmology, University of Birmingham, U.K.
Metabolic, Pediatric, and Systemic Ophthalmology (New York, N.Y. : 1985)
|January 1, 1991
Summary
Patients with neovascular glaucoma, especially those who are debilitated and using topical steroids, face a higher risk of severe intraocular infections like endophthalmitis. This finding highlights a potentially susceptible patient group requiring careful monitoring.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Glaucoma Research
Background:
- Neovascular glaucoma is a severe complication, often resulting from central retinal vein occlusion.
- Evisceration is a surgical procedure for eyes with intractable pain or infection.
Purpose of the Study:
- To investigate the risk factors and outcomes for patients undergoing evisceration, particularly those with neovascular glaucoma.
- To identify specific patient subgroups susceptible to severe intraocular infections.
Main Methods:
- Retrospective analysis of 35 patients who underwent evisceration between 1982 and 1987.
- Review of patient records to determine underlying conditions, treatments, and complications.
Main Results:
- 60% of patients had neovascular glaucoma, primarily due to central retinal vein occlusion.
- 76% of these eyes developed endophthalmitis requiring evisceration.
- 81% of infected patients used topical steroids before developing keratitis and endophthalmitis.
- All 9 debilitated neovascular glaucoma patients developed endophthalmitis, with 78% using topical steroids.
Conclusions:
- Debilitated patients with neovascular glaucoma using topical steroids may be a high-risk group for severe intraocular infections.
- Prompt recognition and management of neovascular glaucoma in susceptible patients are crucial to prevent sight-threatening complications.