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Updated: Jun 25, 2026

Single-port Non-liposuction Endoscopic Axillary Lymph Node Dissection in Breast Cancer Surgery
Published on: April 3, 2026
Sealants after axillary lymph node dissection for breast cancer: good intentions but bad results
Panagiotis Taflampas1, Elias Sanidas, Manousos Christodoulakis
1Breast Cancer Unit, Department of Surgical Oncology, University Hospital of Crete, Herakleion, Greece. taflampas2003@yahoo.gr
Background:
This study was conducted to evaluate the effect of 2 surgical sealants on postsurgical drainage and lymphocele formation after axillary surgery for breast cancer.
Methods:
This was a prospective, randomized study. Seventy-seven consecutive patients with breast cancer were included and randomized into a control group (18F vacuum drain) and 2 study groups (18F vacuum drain plus COSEAL or BioGlue).
Results:
The 3 groups were matched. Neither postsurgical drainage nor time to drain removal was affected by the use of either of the 2 sealants. Although no statistically significant difference in lymphocele formation and wound infection was noted, complications caused by intense foreign-body reaction that led to surgical intervention occurred in both study groups.
Comments:
The use of surgical sealants is not recommended after axillary lymph node dissection for breast cancer. Complications of their use may lead to reoperation.
