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Characterization of antibody response to Pseudomonas aeruginosa in patients with wound infections
E A Trafny1, J Grzybowski, J Patzer
1Department of Microbiology, Military Institute of Hygiene and Epidemiology, Warsaw, Poland.
Microbiology and Immunology
|January 1, 1991
Abstract:
ELISA was used to measure the amount and avidity of IgG antibodies to exotoxin A (ExA) and 7 Fisher's immunotypes of lipopolysaccharide (LPS) in the sera of 13 patients with mild or moderate Pseudomonas aeruginosa infections. Changes in the specificity of tested sera during the course of infection were demonstrated. A statistically significant increase was seen in the amount and avidity of the antibodies to ExA in a majority of the sera, and an increase was seen in amount of antibodies to LPS immunotype 4 in the sera of patients with moderate infections.