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Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples
Published on: January 21, 2018
Food allergens and respiratory symptoms
M Jesenak1, Z Rennerova, E Babusikova
1Department of Pediatrics, Comenius University in Bratislava, Jessenius School of Medicine, Martin, Slovakia. jesenak@gmail.com
Summary
The atopy patch test aids in diagnosing food allergies causing respiratory issues in children. Positive tests for wheat and egg allergies correlate with symptoms like cough, allergic rhino-conjunctivitis, and asthma.
Area of Science:
- Clinical immunology and allergy
- Pediatric respiratory medicine
Background:
- Food allergies can manifest as diverse respiratory symptoms.
- Cellular-mediated immune reactions are implicated in some food allergies.
- The atopy patch test (APT) is a novel diagnostic tool for delayed hypersensitivity.
Purpose of the Study:
- To investigate the prevalence of positive atopy patch tests (APTs) to food and inhalant allergens in children.
- To correlate APT positivity with atopic and non-atopic respiratory symptoms and diseases.
- To assess the diagnostic utility of APTs in pediatric respiratory allergies.
Main Methods:
- Study conducted on an unselected pediatric population.
- Prevalence of positive APTs to food and inhalant allergens was assessed.
- Correlation analysis between APT results and questionnaire-derived respiratory symptoms/diseases.
Main Results:
- Positive APT results for wheat correlated with cough after exertion, allergic rhino-conjunctivitis, and recurrent bronchitis.
- Positive skin reactions to egg were associated with allergic rhino-conjunctivitis and bronchial asthma.
- A significant correlation was observed between positive skin test results and the history of respiratory diseases/symptoms.
Conclusions:
- Food and inhalant allergens are significant contributors to respiratory allergic diseases in children.
- The atopy patch test is a valuable diagnostic tool for identifying food allergies linked to respiratory symptoms.
- Population-level correlations support the use of skin tests in the work-up of pediatric respiratory allergies.
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