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Novel Percutaneous Approach for Deployment of 3D Printed Coronary Stenosis Implants in Swine Models of Ischemic Heart Disease
Published on: February 18, 2020
Successful percutaneous intervention to acute myocardial infarction presenting with typical chest pain in
Ulas Bildirici1, Umut Celikyurt, Ertan Ural
1Kocaeli University Medical Faculty, Department of Cardiology, Interventional Cardiology Research and Application Unit, Kocaeli, Turkey.
Insights
Allograft coronary artery disease (CAD) limits long-term survival in heart transplant recipients. A rare acute myocardial infarction case in a young female cardiac transplant patient was successfully treated with angioplasty.
Area of Science:
- Cardiology
- Transplantation Medicine
- Immunology
Background:
- Allograft coronary artery disease (CAD) significantly impacts long-term survival in cardiac transplant recipients, affecting approximately 50% of patients within five years.
- Allograft CAD can lead to severe complications including congestive heart failure, ventricular arrhythmias, and sudden cardiac death.
Observation:
- Acute coronary syndrome (ACS) is an uncommon presentation of allograft CAD due to cardiac denervation, often resulting in atypical or absent symptoms.
- Cardiac reinnervation in transplant recipients can occur, potentially leading to angina pectoris as a sign of ACS.
Findings:
- This case report details a 27-year-old female cardiac transplant recipient who experienced an acute myocardial infarction.
- The patient underwent successful treatment with percutaneous transluminal coronary angioplasty (PTCA).
Implications:
- This case highlights the importance of considering ACS in cardiac transplant patients, even with atypical presentations.
- Successful intervention with PTCA demonstrates a viable treatment option for acute myocardial infarction in this vulnerable population.
- Early recognition and intervention are crucial for improving outcomes in cardiac transplant recipients with allograft CAD.
Abstract:
Allograft coronary artery disease (CAD) is the main limiting factor of the long-term survival in cardiac transplant recipients. It is present in approximately 50% of patients at 5 years post-transplant. Allograft CAD might result in congestive heart failure, ventricular arrhythmias and sudden cardiac death. Acute coronary syndrome is a rare presentation of allograft CAD, because symptoms are usually atypical or absent as a result of cardiac denervation. However, it should be reminded that reinnervation of the transplanted heart might occur, and angina pectoris could be felt as a sign of an acute coronary syndrome. We present a 27-year-old female cardiac transplant patient with an acute myocardial infarction, who was successfully treated with percutaneous transluminal coronary angioplasty.
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