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Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas

Published on: September 5, 2011

Chorionic villus sampling and hemangiomas.

Lewis B Holmes¹

¹Genetics Unit, MassGeneral Hospital for Children, Boston, Massachusetts 02114, USA. holmes.lewis@mgh.harvard.edu

The Journal of Craniofacial Surgery

|February 17, 2009

Summary

This summary is machine-generated.

Chorionic villus sampling (CVS) may be linked to infantile hemangiomas. This study investigates if hemangiomas in infants exposed to CVS during pregnancy have distinct immunohistologic features compared to unexposed infants.

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Area of Science:

Prenatal Diagnosis
Fetal Development
Dermatology

Background:

Chorionic villus sampling (CVS) is a common prenatal diagnostic technique.
Concerns arose in the 1990s regarding potential fetal risks, including limb deficiencies and vascular disruption defects, particularly with early gestational CVS.
Infantile hemangiomas were observed more frequently in infants exposed to CVS, with potential placental embolization of angioblasts as a proposed mechanism.

Purpose of the Study:

To determine if infantile hemangiomas in infants exposed to CVS exhibit different immunohistologic characteristics compared to those in unexposed infants.
To investigate the potential link between CVS and the development of infantile hemangiomas.

Main Methods:

Comparative immunohistologic analysis of infantile hemangiomas.
Case-control study design comparing infants exposed to CVS with a control group.
Evaluation of specific cellular markers and tissue characteristics.

Main Results:

The abstract does not contain specific results, but poses the question of whether immunohistologic differences exist.
The study aims to compare hemangioma characteristics between CVS-exposed and non-exposed groups.

Conclusions:

The study seeks to clarify the relationship between CVS and infantile hemangiomas by examining their immunohistologic profiles.
Findings could inform risk assessment and management strategies for pregnant individuals undergoing CVS.