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Updated: Jun 25, 2026

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
Published on: February 6, 2020
Covalent capture: merging covalent and noncovalent synthesis
Leonard J Prins1, Paolo Scrimin
1Department of Chemical Sciences, University of Padova and CNR ITM, Padova Section, Via Marzolo 1, 35131 Padova, Italy. leonard.prins@unipd.it
Abstract:
This Review is concerned with the search of molecules to find a suitable partner with whom to form a bond. Whether an initial encounter results in a fixed bond depends on many critical issues, such as reciprocal compatibility in terms of size and shape, complementary reactivity, proper alignment of reactive groups, and medium effects. The chemist acts as the master of ceremony and finds a high reward in the case of a successful marriage. Giotto's painting "The wedding of Mary and Joseph" illustrates the principles of supramolecular chemistry involved.
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