Related Experiment Video
Updated: Jun 25, 2026
Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Validation of a neonatal pain scale adapted to the new practices in caring for preterm newborns
Christophe Milesi1, Gilles Cambonie, Aurelien Jacquot
1Neonatologie, Hopital de la Croix Rousse, Rousse, Lyon, France.
Unlabelled:
BACKGROUND Neonatal pain assessment generally requires access to facial expression. Improved neonatology practices, such as greater protection against bright lights and non-invasive mask ventilation, have made facial observation more difficult.
Objective:
To validate a 'faceless' acute neonatal pain scale (FANS), which does not depend on facial expression.
Methods:
In a prospective, multicentre study, 24-40-week-old neonates were videotaped during a painful procedure (heel prick). Three investigators then scored the pain using FANS and a previously validated scale: DAN (Douleur aiguë du Nouveau-né). FANS is based on assessment of limb movement, cry and autonomic reaction. Reliability was assessed by inter-rater agreement and internal consistency (Cronbach's alpha). Validity was evaluated by agreement between scales (intraclass correlation coefficient (ICC)). The Wilcoxon test evaluated the FANS score differences between conditions. Results are expressed as medians (25th and 75th percentiles). Ranges are presented for outcome parameters.
Results:
From April 2006 to September 2007, 53 preterms of 32 (30-35) gestational weeks and 1500 (1000-2200) g were observed. Cronbach's alpha was 0.72. The ICC was 0.92 (0.9-0.98) for inter-rater agreement and 0.88 (0.76-0.93) for agreement between scales.
Conclusion:
FANS, which is reliable and valid, is the first scale to score pain in preterm newborns when facial expression is not accessible.
