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Related Concept Videos

Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Depression: Overview01:18

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
Surveys02:16

Surveys

Often, psychologists develop surveys as a means of gathering data. Surveys are lists of questions to be answered by research participants, and can be delivered as paper-and-pencil questionnaires, administered electronically, or conducted verbally. Generally, the survey itself can be completed in a short time, and the ease of administering a survey makes it easy to collect data from a large number of people.
Long-term Depression01:05

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Long-term Depression01:03

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over time, all...

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Related Experiment Video

Updated: Jun 25, 2026

A New Method for Inducing a Depression-Like Behavior in Rats
07:57

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

Is suicidality distinguishable from depression? Evidence from a community-based sample.

A Kate Fairweather-Schmidt1, Kaarin J Anstey, Andrew J Mackinnon

  • 1Centre for Mental Health Research, Building 63, Australian National University, ACT, Australia. kate.fairweather-schmidt@anu.edu.au

The Australian and New Zealand Journal of Psychiatry
|February 18, 2009
PubMed
Summary

Suicidality is distinct from depression, though correlated. This relationship remains stable across genders and age groups, indicating suicidality is an independent construct requiring specific assessment.

Related Experiment Videos

Last Updated: Jun 25, 2026

A New Method for Inducing a Depression-Like Behavior in Rats
07:57

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

Area of Science:

  • Psychiatry
  • Psychology
  • Epidemiology

Background:

  • Suicidal behavior is often linked to depression.
  • Limited understanding of suicidality's stability across lifespan and genders.

Purpose of the Study:

  • Investigate if suicidality is a depression symptom or independent.
  • Examine construct stability across age and gender.

Main Methods:

  • Community-based sample (7485 individuals, ages 20-64).
  • Confirmatory factor analysis for model fit and measurement invariance.

Main Results:

  • Two-factor model (depression and suicidality) superior to single-factor.
  • Strict measurement invariance confirmed across gender and age groups.

Conclusions:

  • Suicidality is distinguishable from depression, but correlated.
  • Factorial relationship is stable across genders and age cohorts.
  • Need for assessment tools measuring suicidality independently of depression.