Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Studies for Cardiovascular System III: Serum Lipid Profile01:25

Blood Studies for Cardiovascular System III: Serum Lipid Profile

Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Lipids: Dietary Sources and Requirements01:18

Lipids: Dietary Sources and Requirements

Lipids are an essential component of a balanced human diet. Triglycerides, which make up the majority of dietary lipids, are found in both saturated fats—commonly present in meat, dairy products, and certain tropical plants like coconut, and hydrogenated oils such as margarine and baking shortenings (trans fats)—and unsaturated fats, which are abundant in seeds, nuts, olive oil, and most vegetable oils. The main sources of cholesterol include egg yolks, various meats and organ meats, shellfish,...
Lipid-Lowering Drugs: Statins and Miscellaneous Agents01:20

Lipid-Lowering Drugs: Statins and Miscellaneous Agents

Hyperlipidemia, a medical condition often referred to as high cholesterol, is characterized by abnormally elevated levels of lipids in the bloodstream. When present in excess, these lipids, specifically cholesterol and triglycerides, can lead to serious health complications, often involving cardiovascular diseases. Illnesses like atherosclerosis, heart attacks, and pancreatitis have all been linked to untreated hyperlipidemia. This means controlling and regulating cholesterol and triglyceride...
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
Overview of Lipid Metabolism01:24

Overview of Lipid Metabolism

Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Outcomes of children with severe diabetic ketoacidosis managed outside of a pediatric intensive care unit.

Journal of pediatric endocrinology & metabolism : JPEM·2022
Same author

Pediatric Endocrinologists' Experiences With Continuous Glucose Monitors in Children With Type 1 Diabetes.

Journal of diabetes science and technology·2018
Same author

Use of Sitagliptin With Closed-Loop Technology to Decrease Postprandial Blood Glucose in Type 1 Diabetes.

Journal of diabetes science and technology·2017
Same author

Effect of Marijuana Use on Thyroid Function and Autoimmunity.

Thyroid : official journal of the American Thyroid Association·2016
Same author

Pediatric Type 1 Diabetes: Reducing Admission Rates for Diabetes Ketoacidosis.

Quality management in health care·2016
Same author

Adjuvant Liraglutide and Insulin Versus Insulin Monotherapy in the Closed-Loop System in Type 1 Diabetes: A Randomized Open-Labeled Crossover Design Trial.

Journal of diabetes science and technology·2016
Same journal

Commentary: This Is Not a Drill.

Texas medicine·2021
Same journal

Healthy Determination: Texas Physicians are Finding Better Ways to Address Their Patients' Social Determinants of Health.

Texas medicine·2021
Same journal

Going Local: Accountable Health Organizations Could Help Combat Social Disparities at the Local Level.

Texas medicine·2021
Same journal

Data Driven: Medicaid's Inspector General Focuses on Fraud Prevention, Not Just Prosecution.

Texas medicine·2021
Same journal

Talk to Patients About: Vaccine Adverse Event Reporting System (VAERS).

Texas medicine·2021
Same journal

Obstacles to Clear.

Texas medicine·2021
See all related articles

Related Experiment Video

Updated: Jun 25, 2026

Assessing Whole-Body Lipid-Handling Capacity in Mice
07:57

Assessing Whole-Body Lipid-Handling Capacity in Mice

Published on: November 24, 2020

Hyperlipidemia in children.

Vandana S Raman1, Rubina A Heptulla

  • 1Department of Pediatrics, Division of Endocrinology and Metabolism, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, USA.

Texas Medicine
|February 18, 2009
PubMed
Summary
This summary is machine-generated.

This summary covers clinical assessment and management of childhood hyperlipidemia. It provides strategies for healthcare providers to address high cholesterol in children.

Related Experiment Videos

Last Updated: Jun 25, 2026

Assessing Whole-Body Lipid-Handling Capacity in Mice
07:57

Assessing Whole-Body Lipid-Handling Capacity in Mice

Published on: November 24, 2020

Area of Science:

  • Pediatrics
  • Cardiology
  • Metabolic Disorders

Background:

  • Childhood hyperlipidemia is an emerging public health concern.
  • Early identification and management are crucial for preventing long-term cardiovascular disease.
  • Genetic and lifestyle factors contribute to pediatric dyslipidemia.

Purpose of the Study:

  • To outline current clinical assessment methods for childhood hyperlipidemia.
  • To describe evidence-based management strategies for pediatric high cholesterol.
  • To provide guidance for healthcare professionals on managing this condition.

Main Methods:

  • Review of current clinical guidelines and literature.
  • Discussion of diagnostic criteria and screening protocols.
  • Explanation of therapeutic interventions, including lifestyle modifications and pharmacotherapy.

Main Results:

  • Standardized assessment protocols aid in early detection.
  • Multifaceted management approaches are effective.
  • Lifestyle changes are foundational, with medication as an adjunct when necessary.

Conclusions:

  • Effective management of childhood hyperlipidemia requires a comprehensive approach.
  • Early intervention can mitigate future cardiovascular risks.
  • Healthcare providers need updated strategies for pediatric lipid disorders.