Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

RNA Structure01:23

RNA Structure

Overview
The basic structure of RNA consists of a five-carbon sugar and one of four nitrogenous bases. Although most RNA is single-stranded, it can form complex secondary and tertiary structures. Such structures play essential roles in the regulation of transcription and translation.
Different Types of RNA Have the Same Basic Structure
There are three main types of ribonucleic acid (RNA): messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). All three RNA types consist of a...
RNA Structure01:19

RNA Structure

The basic structure of RNA consists of a string of ribonucleotides attached by phosphodiester bonds. Although most RNA is single-stranded, it can form complex secondary and tertiary structures. Such structures play essential roles in the regulation of transcription and translation.
Different Types of RNA Have the Same Basic Structure
There are three main types of ribonucleic acid (RNA) involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). All three...
RNA Structure01:23

RNA Structure

Overview
The basic structure of RNA consists of a five-carbon sugar and one of four nitrogenous bases. Although most RNA is single-stranded, it can form complex secondary and tertiary structures. Such structures play essential roles in the regulation of transcription and translation.
Different Types of RNA Have the Same Basic Structure
There are three main types of ribonucleic acid (RNA): messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). All three RNA types consist of a...
Riboswitches01:56

Riboswitches

Riboswitches are non-coding mRNA domains that regulate the transcription and translation of downstream genes without the help of proteins. Riboswitches bind directly to a metabolite and can form unique stem-loop or hairpin structures in response to the amount of the metabolite present. They have two distinct regions – a metabolite-binding aptamer and an expression platform.
The aptamer has high specificity for a particular metabolite which allows riboswitches to specifically regulate...
Ribosomal RNA Synthesis02:53

Ribosomal RNA Synthesis

Ribosome synthesis is a highly complex and coordinated process involving more than 200 assembly factors. The synthesis and processing of ribosomal components occurs not only in the nucleolus but also in the nucleoplasm and the cytoplasm of eukaryotic cells.
Ribosome biogenesis begins with the synthesis of 5S and 45S pre-rRNAs by distinct RNA polymerases. The primary transcripts are extensively processed and modified before they are bound and folded by ribosomal proteins and assembly factors,...
Ribosomal RNA Synthesis02:53

Ribosomal RNA Synthesis

Ribosome synthesis is a highly complex and coordinated process involving more than 200 assembly factors. The synthesis and processing of ribosomal components occurs not only in the nucleolus but also in the nucleoplasm and the cytoplasm of eukaryotic cells.
Ribosome biogenesis begins with the synthesis of 5S and 45S pre-rRNAs by distinct RNA polymerases. The primary transcripts are extensively processed and modified before they are bound and folded by ribosomal proteins and assembly factors,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

3D Printing in alloy design to improve biocompatibility in metallic implants.

Materials today (Kidlington, England)·2021
Same author

Nutritional Supplementation of Donors May Improve Outcomes Following the Transfusion of Stored Red Blood Cells.

Journal of dietary supplements·2017
Same author

Uric acid increases erythrocyte aggregation: Implications for cardiovascular disease.

Clinical hemorheology and microcirculation·2015
Same author

Ten year experience of using a novel metabolic protocol in 'off pump' coronary artery bypass revascularization.

Therapeutic advances in cardiovascular disease·2015
Same author

D-ribose aids heart failure patients with preserved ejection fraction and diastolic dysfunction: a pilot study.

Therapeutic advances in cardiovascular disease·2015
Same author

Anomalous right coronary arterial-aortic fistula in an adult sheep.

Veterinary surgery : VS·2014

Related Experiment Video

Updated: Jun 25, 2026

Caffeine Extraction, Enzymatic Activity and Gene Expression of Caffeine Synthase from Plant Cell Suspensions
09:11

Caffeine Extraction, Enzymatic Activity and Gene Expression of Caffeine Synthase from Plant Cell Suspensions

Published on: October 2, 2018

D-ribose--an additive with caffeine.

Jim Herrick1, L M Shecterle, J A St Cyr

  • 1Bioenergy Life Sciences, Inc., 13840 Johnson St. NE, Minneapolis, MN 55304, United States.

Medical Hypotheses
|February 19, 2009
PubMed
Summary
This summary is machine-generated.

D-ribose may mitigate caffeine

More Related Videos

Absolute Quantification of Cell-Free Protein Synthesis Metabolism by Reversed-Phase Liquid Chromatography-Mass Spectrometry
08:06

Absolute Quantification of Cell-Free Protein Synthesis Metabolism by Reversed-Phase Liquid Chromatography-Mass Spectrometry

Published on: October 25, 2019

Functional Characterization of Endogenously Expressed Human RYR1 Variants
07:59

Functional Characterization of Endogenously Expressed Human RYR1 Variants

Published on: June 9, 2021

Related Experiment Videos

Last Updated: Jun 25, 2026

Caffeine Extraction, Enzymatic Activity and Gene Expression of Caffeine Synthase from Plant Cell Suspensions
09:11

Caffeine Extraction, Enzymatic Activity and Gene Expression of Caffeine Synthase from Plant Cell Suspensions

Published on: October 2, 2018

Absolute Quantification of Cell-Free Protein Synthesis Metabolism by Reversed-Phase Liquid Chromatography-Mass Spectrometry
08:06

Absolute Quantification of Cell-Free Protein Synthesis Metabolism by Reversed-Phase Liquid Chromatography-Mass Spectrometry

Published on: October 25, 2019

Functional Characterization of Endogenously Expressed Human RYR1 Variants
07:59

Functional Characterization of Endogenously Expressed Human RYR1 Variants

Published on: June 9, 2021

Area of Science:

  • Biochemistry
  • Human Physiology
  • Nutritional Science

Background:

  • Caffeine is a widely consumed stimulant with known adverse effects like insomnia and nervousness.
  • Caffeine's mechanisms involve adenosine receptor blockade and intracellular calcium release.
  • Existing strategies to reduce caffeine's side effects lack consensus.

Purpose of the Study:

  • To investigate D-ribose as a potential substrate to reduce caffeine's negative effects.
  • To explore D-ribose's role in energy metabolism and cellular processes related to caffeine consumption.

Main Methods:

  • Literature review on caffeine's physiological effects and proposed mechanisms.
  • Analysis of D-ribose's biochemical properties and potential interactions with caffeine.
  • Hypothesizing D-ribose's impact on adenosine levels, calcium flux, and cellular energy.

Main Results:

  • D-ribose may help maintain cellular energy by supporting adenosine triphosphate (ATP) levels.
  • It could potentially modulate extracellular adenosine and intracellular calcium concentrations.
  • D-ribose might alleviate the perceived 'crash' and other adverse effects of caffeine.

Conclusions:

  • D-ribose shows promise in counteracting caffeine's undesirable side effects.
  • It may support cellular energy demands, potentially preserving caffeine's stimulant benefits.
  • Further research is warranted to confirm D-ribose's efficacy with caffeine.