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Related Concept Videos

Other Pulmonary Disorders01:17

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA (lncRNA)...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...

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Related Experiment Video

Updated: Jun 25, 2026

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
11:15

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 20, 2016

[Lung cancer].

Hideaki Mizutani1, Akihiko Gemma

  • 1Dept. of Respiratory Medicine, Nippon Medical School, Tokyo, Japan.

Gan to Kagaku Ryoho. Cancer & Chemotherapy
|February 19, 2009
PubMed
Summary

Lung cancer treatment requires detailed classification beyond small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). Personalized treatment selection depends on factors like gene mutations and histology.

Area of Science:

  • Oncology
  • Medical Genetics

Context:

  • Traditional lung cancer classification into small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) guides initial treatment.
  • Prognosis and treatment response significantly differ between SCLC and NSCLC due to distinct clinical-pathological features.

Purpose:

  • To highlight the limitations of broad NSCLC classification in the era of targeted therapies.
  • To emphasize the necessity for more granular classification in lung cancer treatment selection.

Summary:

  • Modern lung cancer treatment selection necessitates moving beyond the SCLC/NSCLC dichotomy.
  • Factors such as adenocarcinoma presence, ethnicity, gender, smoking history, and specific gene mutations are crucial for effective treatment planning.
  • Recent findings, like the reduced efficacy of pemetrexed in non-squamous cell carcinoma, underscore the need for detailed subtyping.

Related Experiment Videos

Last Updated: Jun 25, 2026

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
11:15

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 20, 2016

Impact:

  • Facilitates personalized medicine approaches in lung cancer care.
  • Improves treatment efficacy by aligning therapies with individual patient profiles and tumor characteristics.
  • Supports the development of more refined diagnostic and therapeutic strategies for lung cancer patients.