Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Exploring the needs of technical developers and stakeholders in point-of-care technology development: a qualitative study.

BMJ open·2026

Same author

Integrated triplex LFIA platform for decentralized molecular subtyping of breast cancer.

RSC advances·2026

Same author

Parallelized droplet microfluidic mechanoporation enables robust and clogging-resistant intracellular gene delivery.

Microsystems & nanoengineering·2026

Same author

Saliva as a Matrix for Primary Care: Feasibility and Scoping of Its Use for Assessment of Nutrition and Inflammation.

Advances in nutrition (Bethesda, Md.)·2026

Same author

Artificial Intelligence-Based Diagnosis of Kaposi Sarcoma Using Digital Photographs in Dark-Skinned Patients in Uganda.

JCO global oncology·2026

Same author

Safe and Efficient CRISPR Genome Editing of Primary Human T Cells Using a Droplet-Based Cell Mechanoporation Platform.

Small (Weinheim an der Bergstrasse, Germany)·2026

Same journal

Controlled encapsulation and droplet size prediction in two-step microfluidic double emulsions.

Lab on a chip·2026

Same journal

A particulate blood-mimicking fluid with physiological biconcave geometry for microscale hemorheology.

Lab on a chip·2026

Same journal

Multicellular sensor arrays fabricated by capillary stamping for pattern-based odor discrimination.

Lab on a chip·2026

Same journal

A real-time microfluidic surveillance system for multiplex detection of heavy metal contamination in wastewater.

Lab on a chip·2026

Same journal

Vision-guided parallel manipulation of cells with optoelectronic tweezers.

Lab on a chip·2026

Same journal

Review of nanofluidic mass transport systems: engineering through physicochemical fields and interfacial properties.

Lab on a chip·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 25, 2026

Early Metamorphic Insertion Technology for Insect Flight Behavior Monitoring

Early Metamorphic Insertion Technology for Insect Flight Behavior Monitoring

Published on: July 12, 2014

Engineering insect flight metabolics using immature stage implanted microfluidics.

Aram J Chung¹, David Erickson

¹Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA.

|February 19, 2009

Summary

This summary is machine-generated.

Researchers engineered insect flight metabolics using microfluidics. This novel method allows on-command control over insect movement by modulating internal amino acid levels, offering new avenues for bio-inspired robotics.

More Related Videos

Delivery of Nucleic Acids through Embryo Microinjection in the Worldwide Agricultural Pest Insect, Ceratitis capitata

Delivery of Nucleic Acids through Embryo Microinjection in the Worldwide Agricultural Pest Insect, Ceratitis capitata

Published on: October 1, 2016

Insect-machine Hybrid System: Remote Radio Control of a Freely Flying Beetle (Mercynorrhina torquata)

Insect-machine Hybrid System: Remote Radio Control of a Freely Flying Beetle (Mercynorrhina torquata)

Published on: September 2, 2016

Related Experiment Videos

Last Updated: Jun 25, 2026

Early Metamorphic Insertion Technology for Insect Flight Behavior Monitoring

Early Metamorphic Insertion Technology for Insect Flight Behavior Monitoring

Published on: July 12, 2014

Delivery of Nucleic Acids through Embryo Microinjection in the Worldwide Agricultural Pest Insect, Ceratitis capitata

Delivery of Nucleic Acids through Embryo Microinjection in the Worldwide Agricultural Pest Insect, Ceratitis capitata

Published on: October 1, 2016

Insect-machine Hybrid System: Remote Radio Control of a Freely Flying Beetle (Mercynorrhina torquata)

Insect-machine Hybrid System: Remote Radio Control of a Freely Flying Beetle (Mercynorrhina torquata)

Published on: September 2, 2016

Area of Science:

Bio-inspired engineering
Neuroscience
Microfluidics

Background:

Replicating insect flight mechanics in micro-aircraft is challenging.
Previous methods used external stimuli (electrical, optical, acoustic) for insect flight control.
Directly engineering insect flight metabolics offers a novel control strategy.

Purpose of the Study:

To develop and demonstrate a method for directly and reversibly engineering insect flight metabolics.
To present a microfluidic device for on-command modulation of internal amino acid levels.
To quantify the impact of metabolic changes on insect flight behavior.

Main Methods:

Implantation of microfluidic devices in immature insects 1-2 days before emergence.
On-command modulation of internal l-glutamic and l-aspartate acid levels via microfluidics.
Monitoring of respiratory CO(2) output to quantify metabolic activity changes.

Main Results:

High survivability (96%) and flight-capable rates (36%) achieved with implanted microfluidic devices.
Demonstrated on-command behavioral changes, including retarded motion and reversible paralysis.
Metabolic activity was successfully modulated, correlating with observed behavioral changes.

Conclusions:

Microfluidic-based metabolic engineering provides a direct and reversible method for controlling insect flight.
This technique offers a new paradigm for studying insect flight control and developing bio-inspired micro-aerial vehicles.
The study highlights the potential of internal metabolic modulation for precise behavioral engineering in insects.