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Updated: Jun 25, 2026
A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies
Published on: July 28, 2020
[Imaging of soft tissue sarcomas: standard approaches and new strategies]
F Berger1, E C Winkler, C Ruderer
1Institut für Klinische Radiologie, Klinikum der Universität München, Campus Grosshadern, Marchioninistrasse 15, Munich, Germany. Frank.Berger@med.uni-muenchen.de
Abstract:
Soft tissue sarcomas are rare malignant neoplasms accounting for only 1% of malignant tumors in adults. Complete surgical resection of the tumor is key for therapeutic success. Comprehensive diagnostic imaging significantly contributes to adequate preoperative planning. With effective targeted molecular pharmacotherapies entering the clinical scenario, functional imaging strategies will have a significant effect on individual risk assessment and will contribute to optimized, noninvasive treatment response monitoring.
Insights
Complete surgical resection is crucial for treating rare soft tissue sarcomas. Advanced imaging aids surgical planning and monitors treatment effectiveness for personalized care.
Area of Science:
- Oncology
- Radiology
Context:
- Soft tissue sarcomas represent rare adult malignancies, comprising 1% of all cancer diagnoses.
- Surgical resection is the primary curative treatment modality.
Purpose:
- To highlight the importance of diagnostic imaging in preoperative planning for soft tissue sarcomas.
- To emphasize the emerging role of functional imaging in risk stratification and noninvasive treatment monitoring.
Summary:
- Complete surgical resection is paramount for successful soft tissue sarcoma treatment.
- Comprehensive diagnostic imaging is essential for effective preoperative planning.
- Functional imaging strategies are becoming vital for personalized risk assessment and monitoring therapeutic response.
Impact:
- Improved surgical outcomes through enhanced preoperative planning.
- Personalized patient management via accurate risk stratification.
- Optimized, noninvasive monitoring of treatment efficacy for soft tissue sarcomas.
