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Updated: Jun 25, 2026
Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
Behaviour of nonresorbable bioactive glass-ceramic implanted into long bone defects: comparison with cancellous
Pavel Sponer1, Karel Urban, Elen Urbanová
1Department of Orthopaedic Surgery, Charles University, University Hospital, 500 05 Hradec Králové, Czech Republic. sponer.p@seznam.cz
Introduction:
The goal of this retrospective study was to compare the long-term results after implantation of the nonresorbable glass-ceramic material and transplantation of the cancellous allografts into the defects of long bones.
Method:
The bone cysts were excochleated and filled using granules of glass-ceramic material or cancellous allografts. Clinical, radiographic and scintigraphic examinations of 30 patients were carried out 2-14 years after their surgery.
Results:
Though signs of complete incorporation allowing full weight-bearing capacity were observed on plain radiographs, we detected pain in six out of nine patients after diaphyseal implantation of nonresorbable glass-ceramic. We found an increase in (99) (m)Tc-methylene diphosphonate uptake on the delayed images in the area of glass-ceramic implantation, mainly in its diaphyseal location. In patients after bone transplantation, the cancellous allografts were completely integrated and the scintigraphic findings were physiological.
Conclusion:
The implantation of the nonresorbable glass-ceramic material into the diaphyseal defects of long bones is not suitable based on our study.
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