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Pre-hospital use of ketamine in paediatric trauma
P P Bredmose1, G Grier, G E Davies
1London Helicopter Emergency Medical Service, Department of Pre-hospital Care, The Royal London Hospital, London, UK.
Insights
Ketamine is a safe and effective option for procedural sedation and analgesia in children during pre-hospital emergency care. This review found no major side effects in pediatric patients receiving ketamine for various injuries.
Area of Science:
- Emergency Medicine
- Pediatric Critical Care
- Pharmacology
Background:
- Pre-hospital care for children requires effective analgesia and sedation.
- Ketamine offers potential benefits for procedural sedation in pediatric emergencies.
Purpose of the Study:
- To evaluate the use and safety of ketamine in pediatric patients by a pre-hospital physician-based service.
- To describe ketamine administration in children under 16 years.
Main Methods:
- Retrospective database review of 164 pediatric patients (<16 years) treated by London's Helicopter Emergency Medical Service.
- Analysis of ketamine dosage, route of administration, co-medications, and patient characteristics.
Main Results:
- Ketamine was administered to children with a median age of 10 years, mostly awake (GCS 15) and non-trapped.
- Common indications included road traffic collisions, burns, and falls for procedural sedation and analgesia.
- No significant adverse events like airway loss or oxygen desaturation were observed.
Conclusions:
- Ketamine appears to be a safe drug for pediatric pre-hospital procedural sedation and analgesia.
- The safety profile in this setting is reassuring, with rare use in trapped children.
- Adequate analgesia and sedation are achievable with ketamine in pediatric emergencies.
Objectives:
To describe the use of ketamine in children by a pre-hospital physician-based service.
Methods:
A five and a half year retrospective database review of all patients aged <16 years who were attended by London's Helicopter Emergency Medical Service and given ketamine.
Results:
One hundred and sixty-four children met the inclusion criteria. The median age was 10 years (range 0-15 years). One hundred and four (63%) had a Glasgow Coma Scale (GCS) of 15 and 153 (93%) had a GCS>8 before administration of ketamine. Patients received from 2 to 150 mg ketamine IV (mean=1.0 mg/kg) and 112 (68%) received concomitant midazolam (0.5-18 mg, mean=0.1 mg/kg). One hundred and forty-one (86%) received ketamine intravenously and 23 (14%) intramuscularly. Only 12 patients (7%) were trapped. The most common mechanisms of injury in those who received ketamine were road traffic collisions, burns and falls.
Conclusion:
The safe delivery of adequate analgesia and appropriate sedation is a priority in paediatric pre-hospital care. Ketamine was predominantly used in awake non-trapped patients with blunt trauma for procedural sedation and analgesia. Detailed database searches did not demonstrate loss of airway, oxygen desaturation or clinically significant emergence reactions after ketamine administration. This study failed to demonstrate any major side effects of the drug and reassured us that the safety profile of the drug in this environment is likely to be satisfactory. The use of ketamine in trapped children was rare.
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