Related Experiment Video
Updated: Jun 25, 2026

Navigating the Mass Spectrometry-Based Proteomic Data Using Free Computational Tools
Published on: August 19, 2025
The HCV serum proteome: a search for fibrosis protein markers
K J Cheung1, K Tilleman, D Deforce
1Department of Hepatology and Gastroenterology, Ghent University Hospital, Ghent, Belgium. kinjip.cheung@ugent.be
Abstract:
Liver fibrosis/cirrhosis is a serious health issue in hepatitis C virus (HCV-) infected patients and is currently diagnosed by the invasive liver biopsy. The aim of this study was to find useful fibrosis markers in HCV-patients' sera of different fibrosis degrees (METAVIR F0-F4) based on proteomics. Serum proteome profiles were created by two-dimensional gel electrophoresis. Profiles were analysed between different degrees of fibrosis (F0-F4) and between early (F0F1) and late (F2F3F4) fibrosis by univariate analyses (P
Related Concept Videos
Cirrhosis II: Pathophysiology
Cirrhosis I: Introduction
Hepatitis

