Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Couette Flow

Couette Flow

Couette flow represents the flow of fluid between two parallel plates, with one plate fixed and the other moving with a constant velocity. This configuration allows for a simplified analysis using the Navier-Stokes equations, which govern fluid motion under conditions of viscosity and incompressibility. For Couette flow, the assumptions include a steady, laminar, incompressible flow with a zero-pressure gradient in the flow direction. This flow type is beneficial for understanding shear-driven...

Laminar Flow

Laminar Flow

Laminar flow represents a smooth, orderly fluid motion where particles move along parallel paths, resulting in minimal mixing between layers. Streamlined particle paths characterize this flow regime and occur under conditions where viscous forces dominate over inertial forces. The distinction between laminar, transitional, and turbulent flow is primarily determined by the Reynolds number, a dimensionless quantity calculated as:

Rapidly Varying Flow

Rapidly Varying Flow

Rapidly varying flow (RVF) in open channels is characterized by abrupt changes in flow depth over a short distance, with the rate of depth change relative to distance often approaching unity. These flows are inherently complex due to their transient and multi-dimensional nature, making exact analysis difficult. However, approximate solutions using simplified models provide valuable insights into their behavior.Key Features of Rapidly Varying FlowRVF is commonly observed in scenarios involving...

Steady, Laminar Flow Between Parallel Plates

Steady, Laminar Flow Between Parallel Plates

Understanding steady, laminar flow between parallel plates is essential for analyzing and designing flow in narrow rectangular channels, commonly found in various water conveyance and drainage systems. The Navier-Stokes equations govern fluid motion and are generally challenging to solve due to their nonlinearity. However, simplifications are possible in certain cases, like the steady laminar flow between parallel plates. For this scenario, we assume steady, incompressible, laminar flow.

Gradually Varying Flow

Gradually Varying Flow

Gradually varying flow (GVF) in open channels describes situations where water depth changes slowly along the channel due to factors like non-uniform bed slope, channel shape variations, or obstructions. This flow type occurs when the depth adjusts gradually to balance gravitational forces, shear forces, and energy requirements, resulting in a low rate of depth change.Characteristics of Gradually Varying FlowGVF is commonly observed in natural streams, rivers, and canals, where flow depth...

General External Flow Characteristics

General External Flow Characteristics

The study of external flow is essential for creating structures and objects that interact efficiently and safely with moving fluids, such as air or water. When a body is immersed in a flowing fluid, it experiences two primary forces: drag, which opposes motion along the flow direction, and lift, which acts perpendicular to the flow. The shape, size, and orientation of the object influence these forces.Streamlined and Blunt Bodies in External FlowObjects in fluid flow are classified as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Human amygdala-like telencephalic organoids model stress circuitry in assembloid systems.

Cell stem cell·2026

Same author

Engineering the blood-brain barrier on chip: advances in preclinical drug penetration and disease modeling.

Advanced drug delivery reviews·2026

Same author

Self-localized ultrafast pencil beam for volumetric multiphoton imaging.

Nature methods·2026

Same author

Nanotrap-AI Integration Enables Ultra-Sensitive Point-of-Care HIV Testing.

ACS nano·2026

Same author

Molecular and clinical disparity of <i>EGFR</i>-mutant non-small cell lung cancer (NSCLC) based on histopathological stage and <i>EGFR</i> molecular subtypes.

Translational lung cancer research·2026

Same author

Regenerative effects of myogenic gene transfected MSC derived exosomes on radiation esophagitis.

Tissue engineering and regenerative medicine·2026

Same journal

Anion-Engineered Organic Electrochemical Transistors With Multi-Timescale Synaptic Dynamics for Task-Adaptive Spiking Neural Networks.

Small (Weinheim an der Bergstrasse, Germany)·2026

Same journal

Dimensional Effect on the Lattice Anharmonicity in Graphene and Graphite.

Small (Weinheim an der Bergstrasse, Germany)·2026

Same journal

A Modular Core-Shell Nanoparticle Platform for Dual-Modal MRI-Luminescence With High Relaxivity.

Small (Weinheim an der Bergstrasse, Germany)·2026

Same journal

Highly Selective Construction of D<sub>2</sub>-Symmetric Chiral Carbon Nanorings and the Diverse Assembly With Fullerenes.

Small (Weinheim an der Bergstrasse, Germany)·2026

Same journal

A Synergistic Process Optimization and Data-Driven Modeling Strategy for Unraveling and Enhancing the Low-Light Response in Back-Contact Solar Cells.

Small (Weinheim an der Bergstrasse, Germany)·2026

Same journal

Porous Hydrogel-Mediated One-Step Selection of Mannoprotein-Targeted Aptamers for Early Diagnosis of Invasive Saccharomyces cerevisiae Infections.

Small (Weinheim an der Bergstrasse, Germany)·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 25, 2026

Assembly and Characterization of an External Driver for the Generation of Sub-Kilohertz Oscillatory Flow in Microchannels

Assembly and Characterization of an External Driver for the Generation of Sub-Kilohertz Oscillatory Flow in Microchannels

Published on: January 28, 2022

Nanointerstice-driven microflow.

Seok Chung¹, Hoyoung Yun, Roger D Kamm

¹Department of Mechanical Engineering, Massachusetts Institute of Technology Cambridge, MA 02139, USA.

Small (Weinheim an Der Bergstrasse, Germany)

|February 20, 2009

Summary

This summary is machine-generated.

Nanointerstices (NI) improve capillary flow in microchannels, overcoming surface changes in plastics like PMMA. This offers a predictable, long-term flow solution for disposable diagnostic devices.

More Related Videos

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

Published on: August 27, 2013

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways

Published on: May 9, 2016

Related Experiment Videos

Last Updated: Jun 25, 2026

Assembly and Characterization of an External Driver for the Generation of Sub-Kilohertz Oscillatory Flow in Microchannels

Assembly and Characterization of an External Driver for the Generation of Sub-Kilohertz Oscillatory Flow in Microchannels

Published on: January 28, 2022

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

Published on: August 27, 2013

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways

Published on: May 9, 2016

Area of Science:

Microfluidics
Materials Science
Surface Chemistry

Background:

Capillary-driven flow is preferred for disposable microfluidic diagnostic devices due to its simplicity and lack of external power requirements.
Hydrophobic plastics like poly(methyl methacrylate) (PMMA) hinder capillary flow and require surface treatments that degrade over time.
Surface treatments on PMMA microchannels can lose hydrophilicity during storage, leading to inconsistent and slow capillary flow.

Purpose of the Study:

To investigate a novel method for achieving consistent and predictable capillary flow in microchannels.
To reduce the dependence of capillary flow on surface characteristics in microfluidic devices.
To offer a stable flow generation technique for commercialized microchannel products.

Main Methods:

Introduction of nanointerstices (NI) on the side walls of microchannels.
Fabrication of microchannels using poly(methyl methacrylate) (PMMA).
Evaluation of capillary flow generation and its dependence on surface characteristics.

Main Results:

Nanointerstices (NI) enable capillary flow generation that is less sensitive to surface properties.
Microchannels incorporating NI demonstrate more consistent and predictable flow compared to untreated or conventionally treated surfaces.
The NI technique provides a viable alternative for reliable flow control in microfluidic applications.

Conclusions:

Nanointerstices (NI) offer a robust solution for generating predictable capillary flow in microchannels.
This technique mitigates issues associated with surface degradation in hydrophobic materials used in microfluidics.
NI flow generation presents a promising approach for enhancing the reliability of disposable diagnostic platforms and other microchannel-based products.