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Updated: Jun 25, 2026

A Porcine Heterotopic Heart Transplantation Protocol for Delivery of Therapeutics to a Cardiac Allograft
Published on: February 14, 2022
Cardiac transplantation in Hawai'i: a summary of the first 21 years
Robert A Hong1, Cathy Bailey, Kelly Kindle
1Department of Medicine, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI, USA. robhong@aloha.net
Insights
Hawai
Area of Science:
- Cardiology and Transplant Surgery
Background:
- This study reviews cardiac transplantation outcomes in Hawai'i between 1987 and 2008.
- It examines the feasibility of maintaining a state-based cardiac transplant program.
Observation:
- A total of 45 cardiac transplantations were performed over a 21-year period.
- Survival rates have shown improvement over time.
Findings:
- Cumulative 1-, 3-, and 5-year survival rates were 73.8%, 70.0%, and 63.2%.
- Recent survival rates (last eight years) improved to 90.0%, 87.5%, and 83.3%.
Implications:
- Despite improved clinical outcomes, low patient volumes challenge program sustainability.
- Addressing financing and referral biases is crucial for the continuation of Hawai'i's cardiac transplant program.
Abstract:
Between 1987 and 2008, 45 patients have undergone cardiac transplantation in Hawai'i. This article summarizes the authors' experiences with cardiac transplantation over this 21-year period. The cumulative 1-, 3- and 5-year survival rates after transplantation have been 73.8%, 70.0%, and 63.2%, respectively. The corresponding survival rates have improved over the last eight years and are now 90.0%, 87.5%, and 83.3%, respectively. Despite clinical improvements, low patient volumes make the maintenance of a state-based program in Hawai'i difficult. Problems with financing and referral biases will need to be addressed if a local program is to continue.

